Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
6 Apr 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Deviations:
no
GLP compliance:
yes
Type of method:
other: capillary tube in a metal block: visual observation

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Physical state: viscous colorless liquid at room temperature (22-23 °C)
- Source and lot/batch No.of test material: Lot 10115
- Expiration date of the lot/batch: 10 Jan 2019
- Purity: 95.6%

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: frozen in darkness

FORM AS APPLIED IN THE TEST: solid. The test material did not liquefy after being brought to room temperature.

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
>= 31.1 - <= 38.2 °C
Atm. press.:
759.7 mm Hg
Decomposition:
no
Remarks on result:
other: Reported as 31.1 ± 0.2 °C to 38.2 ± 0.3 °C

Any other information on results incl. tables

An initial rapid scan was used to determine an approximate melting point. Three definitive melting point tests were then performed. The temperature range from sample collapse/surface sheen to a complete transition to a liquid state was reported as the melting range.

The reference substance, benzophenone, was tested in a melting point capillary alone and in a melting point capillary inserted in a boiling point tube. The measured melting points were nearly identical and within the expected range.

Applicant's summary and conclusion

Conclusions:
A melting range of 31.1 ± 0.2 °C to 38.2 ± 0.3 °C at 759.7 mm Hg was observed for 1,1'-isophthaloylbis(2-methylaziridine) as determined by OECD 102.
Executive summary:

The melting point of 1,1'-isophthaloylbis(2-methylaziridine) was tested using OECD Method 102. A mean melting range of 31.1 ± 0.2 °C to 38.2 ± 0.3 °C at 759.7 mm Hg was reported from three definitive tests. The study was conducted in accordance with a national standard method and was GLP compliant; therefore the study is considered reliable without restrictions.