Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 240-166-3 | CAS number: 16026-16-7
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Acute aquatic data are available for two trophic levels for the test item. The most sensitive endpoint was determined to be algae, with a 72-hour EC50 (growth rate) of 1.21 mg/L based on geometric mean measured concentration. Since the lowest EC50 value from the short-term study is > 1 mg/L, the test substance does not need to be classified for acute aquatic toxicity.
Chronic toxicity data are only available for algae for the substance. The lowest 72-hour NOEC for growth rate inhibition was 0.120 mg/L base on geometric mean concentrations. In situation when the chronic toxicity data are only available for one trophic level, the subsequent step is to combine two types of information, i.e. acute aquatic toxicity data and environmental fate data (degradability and bioaccumulation data) and classify according to the most stringent outcome. The lowest EC50 value from the short-term study is 1.21 mg/L based on growth rate of algae. Calcium bis[(Z)-N-methyl-N-(1-oxo-9-octadecenyl)aminoacetate] is predicted to be readily biodegradable based on data available for the read across substance, N-methyl-N-(C18-(unsaturated)alkanoyl)glycine (EC 701-177-3). The read across substance achieved 85.2% degradation based on CO2 evolution after 28 days, therefore it was concluded that the test item is readily biodegradable. The log Kow of Calcium bis[(Z)-N-methyl-N-(1-oxo-9-octadecenyl)aminoacetate] was determined to be >6.2 which is above a cut-off value of log Kow ≥ 4 indicating the potential for bioaccumulation.
The same classification is reached based on the algal NOEC of 0.1 - 1 mg/L for a readily biodegradable substance and where the lowest EC50 is in a range of 1 - 10 mg/L, the substance is expected to be readily biodegradable, however its log Kow of ≥ 4 indicates bioaccumulation potential. Therefore, Calcium bis[(Z)-N-methyl-N-(1-oxo-9-octadecenyl)aminoacetate] is classified Aquatic Chronic Category 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
