Registration Dossier
Registration Dossier
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EC number: 219-698-5 | CAS number: 2499-95-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 19-23, 1983
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPP 72-1 (Fish Acute Toxicity Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 0.72, 1.1, 1.69, 2.60, 4.00 mg/L (nominal)
- Sampling method: sampling at approx mid-depth at 0, 24, 48, 72 and 96 hr
- Sample storage conditions before analysis:All samples were analyzed immediately or adequately preserved for later analysis. - Vehicle:
- no
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- TEST ORGANISM
- Common name:Fathead minnow
- Strain:
- Source:U.S. EPAenvironmental research lab-Duluth and University of Wisconsin-Superior.
- Age at study initiation (mean and range, SD): 34 Day
- Length at study initiation (length definition, mean, range and SD): 22.8 mm
- Weight at study initiation (mean and range, SD): 0.157 grams
- Method of breeding:natural spawn/fertilized embryos attached to subtrates, removed dailty and hatched in temp controlled bath
- Maintenance of the brood fish:
ACCLIMATION not specified
- Acclimation period:
- Acclimation conditions (same as test or not):
- Type and amount of food during acclimation:
- Feeding frequency during acclimation:
- Health during acclimation (any mortality observed):
FEEDING DURING TEST no feeding during test - Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 d
- Hardness:
- 45.3 mg/L as CaCO3
- Test temperature:
- 24.2 C
- pH:
- 7.58 (+/-0.3)
- Dissolved oxygen:
- 6.5 (+/-0.06)
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1.09 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 96 hr LC50 for fathead minnows exposed to n-hexyl acrylate is 1.09 mg/L.
Reference
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1.09 mg/L
Additional information
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