Registration Dossier
Registration Dossier
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EC number: 241-555-0 | CAS number: 17586-94-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Deviations:
- no
- GLP compliance:
- yes
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Reference substance name:
- Dioctyltin di(acetate)
- EC Number:
- 241-555-0
- EC Name:
- Dioctyltin di(acetate)
- Cas Number:
- 17586-94-6
- Molecular formula:
- C20H40O4Sn
- IUPAC Name:
- dioctyltin di(acetate)
- Test material form:
- liquid
- Details on test material:
- TK 229 740293
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: HsdHan WIST
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- corn oil
- Doses:
- 2000 mg/kg bw
- No. of animals per sex per dose:
- 5
- Control animals:
- no
Results and discussion
Effect levels
- Key result
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- 0
- Clinical signs:
- piloerection increased activity in two animals
- Body weight:
- see study report
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Conclusions:
- LD50 > 2000 mg/kg bw
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