Registration Dossier
Registration Dossier
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EC number: 218-345-2 | CAS number: 2128-93-0
Endpoint summary
Administrative data
Description of key information
The hydrolysis study has been waivered because the test substance is highly insoluble in water and therefore the study is technically unfeasible.
A reliable and valid study (Klimisch 1) was performed to assess the adsorption coefficient of the test substance according to the OECD guideline 121 (Partition coefficient (n-octanol/water) by high performance liquid chromatography (HPLC) method). At neutral pH, at 35˚C the Koc was determined to be 37,000 and the log Koc was 4.57.
A reliable study (Klimisch 1) assessed ready biodegradability using a standard method in compliance with OECD guideline 301B, according to GLP. After 28 days a maximum of 2% degradation was observed, therefore, the test substance should be considered as not readily biodegradable.
However, it should be noted that this study was run at a concentration of 13.5mg/L, based on molecular formula and is considered to be greatly over the limit of solubility (0.0736mg/L). Due to this, it is unlikely that the test substance would have been bioavailable for biodegradation by the microbes.
Additional information
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