9-[2-(ethoxycarbonyl)phenyl]-3,6-bis(ethylamino)-2,7-dimethylxanthylium chloride

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-03-27 to 2018-07-30

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

dynamic method

Key result

Atm. press.:

1 007 hPa

Decomposition:

yes

Decomp. temp.:

ca. 220 °C

Remarks on result:

other: The test item has no boiling point up to the decomposition, starting at approx. 220 °C.

Results

In the temperature range of 220 - 250 °C, 250 - 280 °C and 290 - 320 °C three endothermic effects were observed. In the temperature range of 320 - 370 °C an exothermic effect was observed, with a decomposition energy of approx. -40 J/g.

Table 1: Results of the DSC-measurements

No.	Sample	Onset of Effect/ °C	Range of effect/ °C	Weight loss/ mg	Atmospheric presure/ hPa
PN15597	10.76	229.13 260.03 310.84	220 – 250 (endo) 250 – 280 (endo) 290 – 320 (endo) 320 – 360 (exo)	5.27	1007.4
PN15598	10.91	229.62 257.10 307.42	220 – 250 (endo) 250 – 280 (endo) 290 – 320 (endo) 320 – 370 (exo)	4.48	1007.4

During the heating phase three endothermic effects were observed, which can't be clearly assigned to a melting of the test item. Thus, the capillary method was performed for a verification of the DSC-measurements.

Three capillaries were filled with the test item up to a height of 4 - 6 mm. The capillaries were heated up from 30 to 200 °C with a constant heating rate of 10 K/min and from 200 to 400 °C with a constant heating rate of 10 K/min in the BÜCHI melting point apparatus. The test item was visually observed while increasing the temperature.

The melting of the test item could be observed at approx. 212 °C. The test item darkened at approx. 220 °C and its colour changed to black at approx. 280 °C. No boiling of the test item could be observed up to the decomposition of the test item.

Combining the results of the measurements, the first endothermic effect in the DSC in the temperature range of 220 to 250 °C can be assigned to a melting of the test item. As the onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 229.4 °C, the test item has a melting point of 229.4 °C under decomposition, which starts at approx. 220 °C.

No boiling of the test item could be observed up to the decomposition, starting at approx. 220 °C.

Conclusions:

The substance decomposes before boiling.

Executive summary:

The test item has no boiling point up to the decomposition, starting at approx. 220 °C at atmospheric pressure (1007 hPa) in an open aluminium crucible as determined by differential scanning calorimetry and confirmed by the capillary method according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).

Description of key information

The substance decomposes before boiling.

Additional information

The test item has no boiling point up to the decomposition, starting at approx. 220 °C at atmospheric pressure (1007 hPa) in an open aluminium crucible as determined by differential scanning calorimetry and confirmed by the capillary method according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).