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Diss Factsheets
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EC number: 227-774-4 | CAS number: 5977-14-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- Test wa performed acc to DIN 38412 part 25, similar to OECD 302 B; no GLP
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 May 1989 - 14 June 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- yes
- Remarks:
- origins of the sludge and test substance concentration
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.9 (Biodegradation: Zahn-Wellens Test)
- Deviations:
- yes
- Remarks:
- already mentioned
- Principles of method if other than guideline:
- DIN 38 412 Part 25 (1984). This method is corresponding with small differences to the Guideline OECD 302B and EU Test method C.9.
- GLP compliance:
- no
- Remarks:
- newly generated from 1989 report
- Specific details on test material used for the study:
- Test substance dissolved in approx. 30% in aqueous solution
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, industrial, non-adapted
- Details on inoculum:
- Mixture of activated sludge from the sewage treatment plant from one industrial site and activated sludge from the other industrial site.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 357.9 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Stock solution:
5 g 30% acetoacetamide solution were mixed with 1800 ml de-ionized water, the pH adjusted from 6.9 to 7.1. This batch was stirred over a period of 24 hours at 22°C. The resulting clear solution was filled up with de-ionized water to a final volume of 2000 ml and used as stock solution.
Inoculum:
Washing the sediment from the activated sludge two times by centrifuging and resuspending in mineral medium. 12 g/L (=1240 mg dry mass/L) was used for the batch.12 g/L of wet centrifuged sludge was used as inoculum.
241 ml/L stock solution was added. Test item concentration: 357.9 mg/L - Reference substance:
- diethylene glycol
- Remarks:
- 271.6 mg DOC/L
- Test performance:
- During the first 7 days of the test the DOC exhaustion achieved >70% of the carbon content of the added test substance, but during the following 7 days the rate of degradation stayed at the plateau in the range of 70% to 72%.
- Parameter:
- % degradation (DOC removal)
- Value:
- 32
- Sampling time:
- 1 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 70
- Sampling time:
- 9 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 68
- Sampling time:
- 21 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 64
- Sampling time:
- 28 d
- Remarks on result:
- other: inherently biodegradable
- Details on results:
- The results were confirmed by additionally conducted COD control analyses. The analysis of the COD before adding the inoculum resulted in a start value of 510 mg/L COD from the test substance in the test batch. The final COD (28 days, test minus blank) was 160 mg/L, corresponding to 69% elimination.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Acetoacetamide (30% solution) is inherently biodegradable under the conditions of the zahn-Wellens Test.
- Executive summary:
A 30% aequous solution of acetoacetamide was tested for inherent biodegradation in the Zahn-Wellens-test by measuring the DOC disappearance. During the first 7 days of the test the DOC exhaustion achieved > 70% of the carbon content of the added test substance, but the following day the rate of degradation staye at the plateau in the range 70 - 72%. The results were confirmed by additionally conducted COD control analyzes. COD at the start was 510 mg/L and 160 mg/L after 28 days, corresponding to an elimination of about 69%.
Acetoacetamide (30% solution) is inherently biodegradable under the conditions of the zahn-Wellens Test.
Reference
Description of key information
Acetoacetamide (30% solution) is inherently biodegradable under the conditions of the zahn-Wellens Test.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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