Registration Dossier
Registration Dossier
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EC number: 259-952-2 | CAS number: 56038-13-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- GLP compliance:
- not specified
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. -0.51
- Temp.:
- 20 °C
- Remarks on result:
- other: pH was not measured
- Details on results:
- Results for the octanol-water partition coefficients of sucralose are: Measured log Pow = -0.51 +/- 0.03
- Conclusions:
- The log Pow of Sucralose was measured in accordance to the EPA "Shake Flask" method (EPA Test Guidelines "Partition Coefficient (n-Octanol/Water), Estimitation by Liquid Chromatography" OPPTS 830.7570, EPA 712-C-96-040, August 1996) .The measured log Pow of Sucralose is -0.51 +/- 0.03.
Reference
Description of key information
The log Pow of Sucralose was measured in accordance to the EPA "Shake Flask" method (EPA Test Guidelines "Partition Coefficient (n-Octanol/Water), Estimitation by Liquid Chromatography" OPPTS 830.7570, EPA 712-C-96-040, August 1996). The measured log Pow of Sucralose is -0.51 +/- 0.03.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.51
- at the temperature of:
- 20 °C
Additional information
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