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Diss Factsheets
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EC number: 204-527-9 | CAS number: 122-19-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- From March 18, 1999 to April 30, 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study results have been assigned a validity of 2, due to the very high concentrations used of the test substance (0.5g test substance for 1g soil) causing extrapolations to lower concentrations to be less accurate. Adsorption is likely to be higher at lower concentrations than suggested by the outcome of this study.
- Justification for type of information:
- Refer to the section 13 of IUCLID dataset for details on the read across justification. The algae study with the read across substance is considered sufficient to fulfil the information requirements as further explained in the provided endpoint summary.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- batch equilibrium method
- Media:
- soil
- Test temperature:
- room temperature
- Analytical monitoring:
- yes
- Key result
- Type:
- other: Kadsoc (soil 1)
- Value:
- 18 251 L/kg
- Key result
- Type:
- other: Kadsoc (soil 2)
- Value:
- 16 679 L/kg
- Key result
- Type:
- other: Kadsoc (soil 3)
- Value:
- 812 943 L/kg
- Adsorption and desorption constants:
- -soil 1: Kfads = 630 ; soil 2: Kfads = 1543; soil 3: Kfads = 2032
-soil 1: Kfdes = 2828 ; soil 2: Kfdes = 6795; soil 3: Kfdes = 2778;
-soil 1: Kadsoc = 18251; soil 2: Kadsoc = 16679; soil 3: Kadsoc = 812943
Kfads / Kfdes: soil 1: 0.22; soil 2: 0.23; soil 3: 0.73 - Validity criteria fulfilled:
- yes
- Conclusions:
- Based on the results fo the read across study, the test substance is considered to be highly adsorbed onto soil, therefore it could be classified as immobile.
- Executive summary:
A study was conducted to determine the adsorption / desorption of the read across substance, C12-16 ADBAC (active: 51.7%), according to OECD Guideline 106, in compliance with GLP. The soil adsorption / desorption properties were evaluated using the batch equilibrium method. The test substance adsorbed onto soil (soil 1: Kadsoc = 18,251; soil 2: Kadsoc = 16,679; soil 3: Kadsoc = 812,943) and did not desorb easily for the three soil types used. The desorption coefficients (Kdoc) were determined to be 81971, 73459 and 1111200 for soils 1, 2 and 3 respectively. The mean Koc was calculated to be 282,624.3 L/kg. The high concentrations of test substance used in the study (0.5 g test substance for 1 g soil) led to a less accurate extrapolation to lower concentrations. Adsorption is likely to be higher at lower concentrations than suggested by the outcome of this study. Under the conditions of the study, the read across substance adsorbed onto soil and did not desorb easily for the three soil types used, therefore it could be classified as immobile (Geffke, 1999).Based on the results of the read across study, a similar high adsorption potential can be expected for the test substance, C18 ADBAC.
Reference
Test concentrations:
- Euro soil 3: 20 mg/L,
- Euro soil 5: 50 mg/L,
- Euro soil 6: 50 mg/L.
Analysis of the active substance by means of spectrophotometry.
Freundlich (Kads(F) isotherm for adsorption:
Euro log 1/n r^2 soil Kads(F)
____________________________
3 2.7991 0.773 0.9898
5 3.1883 0.7226 0.9619
6 3.308 0.7709 0.9592
Freundlich (Kdes(F) isotherm for desorption:
Euro log 1/n r^2 soil Kdes(F)
_____________________________
3 3.4515 0.5353 0.988
5 3.8322 0.5762 0.9928
6 3.4437 0.7291 0.9984
Description of key information
Based on the results of the read across study, the test substance is considered to be highly adsorbed onto soil, therefore it could be classified as immobile.
Key value for chemical safety assessment
- Koc at 20 °C:
- 282 624.3
Additional information
A study was conducted to determine the adsorption / desorption of the read across substance, C12-16 ADBAC (active: 51.7%), according to OECD Guideline 106, in compliance with GLP. The soil adsorption / desorption properties were evaluated using the batch equilibrium method. The test substance adsorbed onto soil (soil 1: Kadsoc = 18,251; soil 2: Kadsoc = 16,679; soil 3: Kadsoc = 812,943) and did not desorb easily for the three soil types used. The desorption coefficients (Kdoc) were determined to be 81971, 73459 and 1111200 for soils 1, 2 and 3 respectively. The mean Koc was calculated to be 282,624.3 L/kg. The high concentrations of test substance used in the study (0.5 g test substance for 1 g soil) led to a less accurate extrapolation to lower concentrations. Adsorption is likely to be higher at lower concentrations than suggested by the outcome of this study. Under the conditions of the study, the read across substance adsorbed onto soil and did not desorb easily for the three soil types used, therefore it could be classified as immobile (Geffke, 1999). Based on the results of the read across study, a similar high adsorption potential can be expected for the test substance, C18 ADBAC.
[LogKoc: 5.45]
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