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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20 to 24 February 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Remarks:
Staatliches Gewerbeaufsichtsamt Hildesheim, Germany
Type of method:
flask method
Test material information:
Composition 1
Key result
Water solubility:
35.3 g/L
Incubation duration:
>= 24 - <= 72 h
Temp.:
20 °C
pH:
4.1

The following table reports the results of the water solubility test.

 

Preincubation time

Replicate No.

Concentration [g/L] *

Mean [g/L]

24 h

1

35.1

35.5

2

35.9

48 h

1

34.7

35.1

2

35.4

72 h

1

35.9

35.2

2

34.4

Mean (24 - 72 h)

35.3

Deviation [%] (24 - 72 h)

1.3

* Mean value of two injections, dilution factor of 333.3 and exact weight of the standard taken into account

 

The temperature during the pre-incubation and the thermostatisation phase resulted to be 30.06 ± 0.09 °C and 20.00 ± 0.05 °C, respectively.

 

A mean pH-value of 4.1 was determined with the remaining test item mixtures in the original test vessels, which were kept constant at 20 ± 0.5 °C.

 

The test samples showed no Tyndall-Effect.

 

 

Conclusions

The solubility of the test item was determined at 20 ± 0.5 °C to be 35.3 g/L (pH 4.1).

Conclusions:
A water solubility value of 35.3 g/L (at 20 °C, pH = 4.1) was determined for the test substance according to OECD 105.

Description of key information

Water solubility: 35.2 g/L at 20 °C, pH 4.1 (EU Method A.6., flask method)

Key value for chemical safety assessment

Water solubility:
35.2 g/L
at the temperature of:
20 °C

Additional information