Fatty acids tall-oil, reaction products with acrylic acid, potassium salt

Solubility in organic solvents / fat solubility

Link to relevant study record(s)

Reference

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Qualifier:

according to guideline

Guideline:

other: Modified flask method based on Method A.6 Water solubility of Commission Regulation (EC) No 440/2008 and Method 105 of the OECD Guidelines for Testing od Chemicals

GLP compliance:

yes (incl. QA statement)

Key result

Medium:

n-octanol

Solubility:

>= 52.9 - <= 54.9 other: % w/w

Temp.:

20 °C

Medium:

n-octanol

Solubility:

>= 529 - <= 549 g/L

Temp.:

20 °C

Remarks on result:

other: assuming a relative density of ~1 for saturated solution in n-octanol

The sample concentrations and observations are shown in the following table:

Sample	Conc. (% w/w)	Observations
1	24.9%	Clear yellow liquid
2	27.4%	Clear yellow liquid
3	29.1%	Clear yellow liquid
4	31.0%	Clear yellow liquid, slightly more viscous than sample 3
5	33.1%	Clear yellow liquid, slightly more viscous than sample 4
6	34.9%	Clear yellow liquid, slightly more viscous than sample 5
7	34.8%	Amber colored liquid
8	37.1%	Amber colored liquid, slightly more viscous than sample 7
9	39.0%	Amber colored liquid, slightly more viscous than sample 8
10	40.9%	Amber colored liquid, slightly more viscous than sample 9
11	42.9%	Amber colored liquid, slightly more viscous than sample 10
12	45.0%	Amber colored liquid, slightly more viscous than sample 11
13	45.0%	Amber transparent liquid
14	46.9%	Amber transparent liquid, slightly more viscous than sample 13
15	48.9%	Amber transparent liquid, slightly more viscous than sample 14
16	50.9%	Amber transparent liquid, slightly more viscous than sample 15
17	52.9%	Amber transparent liquid, slightly more viscous than sample 16
18	54.9%	Amber transparent liquid with and amber solid / gel at the bottom

Conclusions:

The solubility of the test item in n-octanol has been determined to be in the range 52.9 to 54.9% w/w at 20.0 ±0.5 °C.

Executive summary:

The determination of the octanol solubility of the test item was carried out by visual assessment, using a modified flask method based on Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

The standard flask shake method was not applicable to this test item due to the high saturation level. A range of sample concentrations were prepared to visually assess the point at which saturation was reached.

The solubility of the test item in n-octanol has been determined to be in the range 52.9 to 54.9% w/w at 20.0 ±0.5 °C.

Description of key information

The determination of the octanol solubility of the test item was carried out by visual assessment, using a modified flask method based on Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

The standard flask shake method was not applicable to this test item due to the high saturation level. A range of sample concentrations were prepared to visually assess the point at which saturation was reached.

The solubility of the test item in n-octanol has been determined to be in the range 52.9 to 54.9% w/w at 20.0 ±0.5 °C.