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Diss Factsheets
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EC number: 201-112-4 | CAS number: 78-39-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2017-06-13 to 2017-06-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- method according to Siwoloboff
- Key result
- Boiling pt.:
- 140.3 °C
- Atm. press.:
- 1 013.25 hPa
- Decomposition:
- no
- Conclusions:
- The boiling point of the test item was determined to be 140.3 ± 0.5 °C (413.4 ± 0.5 K) at 1013.25 hPa.
- Executive summary:
The study was performed according to OECD test guideline 103 and Regulation (EC) No. 440/2008 method A.2 in order to determine the boiling point of the test item by using the Siwoloboff method. During the determination no visual changes of the test item were observed. The mean boiling point of the test item was determined to be 140.3 ± 0.5 °C (corresponding to 413.4 ± 0.5 K). The value was calculated from two independent determinations, corrected to the standard pressure of 1013.25 hPa by using the Sidney-Young equation.
Reference
Pre-Test
Formation of the bubble was observed at 128 °C. At 148 °C the bubble chain was visible and the burner was turned off. The chain broke at 139.9 °C. After cooling down no visual changes were observed.
Method following Siwoloboff (Main Test)
The measured values and all observations are presented in the following table.
Table 1: Measured values
Determination | Boiling Point | Atmospheric Pressure |
First determination | 139.1 °C (412.3 K) | 98844 Pa |
Second determination | 139.6 °C (412.8 K) | 98252 Pa |
Table 2: Observations
Observations | First determination |
Second determination |
Individual bubble visible | 133 °C | 135 °C |
Bubble chain; turned off heating plate | 144.6 °C | 144.5 °C |
After cooling down | No visual changes were observed |
No visual changes were observed |
Evaluation
The boiling temperature at standard pressure can be calculated following the equation of Sidney-Young (only for small pressure deviations):
Tn= T+(fT*Δp)
with
Tn =boiling point at 101.325 kPa in K
T = measured boiling point in K
fT= rate of change of boiling temperature with pressure in K/kPa (temperature-related correction factor)
Δp = (101.325 - p) in kPa
p = measured atmospheric pressure in kPa
The temperature-related correction factor (fT) was calculated as 0.34 K/kPa for all boiling point values (412.3 K and 412.8 K) using the following equation:
fT= 0.000843636*T (in K) - 0.008984727
The result is calculated as mean of the two values of the duplicate determination.
Table 3: Corrected values following Sidney-Young
Boiling point | Pressure in Pa | Corrected boiling point |
|
First determination | 139.1 °C (412.3 K) |
98844 Pa | 139.94 °C (413.09 K) |
Second determination | 139.6 °C (412.8 K) |
98252 Pa | 140.64 °C (413.79 K) |
Mean | 140.3 °C |
Mean ± standard deviation (after correction following Sydney-Young) = 140.3 ± 0.5 °C (413.4 ± 0.5 K) at standard pressure (101.325 kPa).
Description of key information
The boiling point of the test item was determined to be 140.3 ± 0.5 °C (413.4 ± 0.5 K) at 1013.25 hPa.
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 140.3 °C
Additional information
The study was performed according toOECD test guideline 103 and Regulation (EC) No. 440/2008 method A.2 in order to determine the boiling point of the test item by using the Siwoloboff method. During the determination no visual changes of the test item were observed. The mean boiling point of the test item was determined to be 140.3 ± 0.5 °C (corresponding to 413.4 ± 0.5 K). The value was calculatedfrom two independent determinations, corrected to the standard pressure of 1013.25 hPa by using the Sidney-Young equation (reference 4.3-1).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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