Registration Dossier
Registration Dossier
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EC number: 202-818-5 | CAS number: 100-09-4
Endpoint summary
Administrative data
Description of key information
Additional information
No data are available on the biodegradation in water of p-anisic-acid (CAS No. 100-09-4). Therefore data from the analogue substance sodium anisate (CAS 536-45-8) were used for read across. This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. This read-across is justified in within the analogue justification in IUCLID Section 13.
One experimental study according to OECD 301 F indicates that the substance sodium anisate (CAS 536-45-8) is readily biodegradable according to the OECD criteria. A degradation of 89% was recorded after 28 d. The measured octanol/water partition coefficient (log Pow of 1.96) is low, indicating a low potential for bioaccumulation. In accordance with column 2 of Regulation (EC) 1907/2006 Annex VIII the testing of adsorption is not required since the substance can be expected to have a low potential for adsorption based on the low log Pow.
There is no study available on hydrolysis as a function of pH with the substance sodium anisate (CAS No. 536-45 -8). In accordance with Regulation (EC) 1907/2006, Annex VIII Column 2, a test for hydrolysis as a function of pH does not need to be performed if the substance is readily biodegradable.
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