Registration Dossier
Registration Dossier
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EC number: 946-512-6 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The IC50 value for inhibition of respiration rate is considered as the most representative value for the toxicity in wastewater treatment systems. Therefore, the toxicity to microorganisms of the target substance is conservatively set to IC50 of 19 mg/L based on read-across from C16 TMA bromide. The IC50 value 19 mg/l, reported will be used for derivation of PNEC (stp).
Key value for chemical safety assessment
- EC50 for microorganisms:
- 19 mg/L
Additional information
Data on toxicity to microorganisms were obtained for sludge inhibition and for effects on metabolism of microorganisms in a standard test with Photobacterium phosphoreum. Compared to the studies on inhibition of microorganisms in sludge, studies on toxicity in low-biomass test systems have generally indicated much higher toxicity under these conditions. In most cases the microbial populations have not been acclimated by previous exposure to the substances. Therefore the significance of these tests is doubtful for representing the toxicity in wastewater treatment systems.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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