N,N-bis(2-hydroxyethyl)glycine

Density

Administrative data

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 23 January 2017 to 16 March 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Version / remarks:

2008

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

2012

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)

Version / remarks:

2002

Deviations:

no

GLP compliance:

yes

Type of method:

air comparison pycnometer (for solids)

Test material

Test material information

Constituent 1

Reference substance name:

N,N-bis(2-hydroxyethyl)glycine

EC Number:

205-755-1

EC Name:

N,N-bis(2-hydroxyethyl)glycine

Cas Number:

150-25-4

Molecular formula:

C6H13NO4

IUPAC Name:

N,N-bis(2-hydroxyethyl)glycine

impurity 1

Reference substance name:

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

EC Number:

205-759-3

EC Name:

N-(2-hydroxyethyl)ethylenediaminetriacetic acid

Cas Number:

150-39-0

Molecular formula:

C10H18N2O7

IUPAC Name:

N-{2-[bis(carboxymethyl)amino]ethyl}-N-(2-hydroxyethyl)glycine

impurity 2

Reference substance name:

Not specified

IUPAC Name:

Not specified

impurity 3

Reference substance name:

Water

EC Number:

231-791-2

EC Name:

Water

Cas Number:

7732-18-5

Molecular formula:

H2O

IUPAC Name:

Dihydrogen oxide

Test material form:

solid: crystalline

Details on test material:

Appearance: white crystalline powder
Storage conditions: at room temperature protected from light

Specific details on test material used for the study:

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
Test material was reduced by grinding using a mortar and dried in a desiccator under vacuum using silicagel as the drying agent at 20°C for 46 hours.

Dynamic viscosity of test material:

not applicable (substance is a solid)

Results and discussion

Density

Density 1

Key result

Type:

relative density

Density:

1.37 other: no dimension

Temp.:

20 °C

Remarks on result:

other: D 20 /4

Density 2

Key result

Type:

density

Density:

1.37 g/cm³

Temp.:

20 °C

Any other information on results incl. tables

Relative density:

Experiment 1: 1.372

Experiment 2: 1.375

Mean: 1.37

Applicant's summary and conclusion

Conclusions:

The relative density D20/4 of the substance was determined to be 1.37.

Executive summary:

The density of the substance was determined using a gas comparison pycnometer in a GLP study according to EC A.3, OECD 109 and OPPTS 830.7300. The relative density D20/4 was determined in duplicate at 20°C obtaining a mean value of 1.37.