Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term repeated dose toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1975

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
1,1-diethoxyethane
EC Number:
203-310-6
EC Name:
1,1-diethoxyethane
Cas Number:
105-57-7
Molecular formula:
C6H14O2
IUPAC Name:
1,1-diethoxyethane
Test material form:
liquid

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: feed
Duration of treatment / exposure:
6 days
Doses / concentrations
Dose / conc.:
5 other: % of the diet

Results and discussion

Any other information on results incl. tables

No detrimental effects were observed.

Applicant's summary and conclusion

Executive summary:

The review cited the results of Yoshida M. et al. [1], in which no detrimental effects have been observed.

[1] Yoshida, M., Ikumo, H. & Suzuki, O. (1971). Evaluation of available energy of aliphatic chemicals by rats. An application of bioassay of energy to mono-gastric animal. Agric. bioi Chem. 35, 1208.