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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
laser
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
[29H,31H-phthalocyaninato-N29,N30,N31,N32]cobalt
EC Number:
222-012-7
EC Name:
[29H,31H-phthalocyaninato-N29,N30,N31,N32]cobalt
Cas Number:
3317-67-7
Molecular formula:
C32H16N8Co
IUPAC Name:
[29H,31H-phthalocyaninato-N29,N30,N31,N32]cobalt

Results and discussion

Particle sizeopen allclose all
Percentile:
other: D5
Mean:
2.8 µm
Remarks on result:
other: SD not provided
Percentile:
D10
Mean:
3.77 µm
Remarks on result:
other: SD not provided
Percentile:
D50
Mean:
15.4 µm
Remarks on result:
other: SD not provided
Percentile:
D90
Mean:
742 µm
Remarks on result:
other: SD not provided
Percentile:
D95
Mean:
1 240 µm
Remarks on result:
other: SD not provided

Any other information on results incl. tables

< 100 µm (inhalable fraction): 70%

< 10 µm (mid-range for thoracic fraction): ~40%

< 4 µm (mid-range for respirable fraction) : ~11%

bimodal size distribution

Applicant's summary and conclusion

Conclusions:
The test item is a fine powder with a bimodal particle size distribution. Upon inhalation, most particles would be inhalable (70% smaller than 100 µm) and a significant part would reach the thorax (40% smaller than 10 µm).