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EC number: 220-168-0 | CAS number: 2650-18-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.1 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.01 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 0.1 mg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.363 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.036 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 1 mg/kg soil dw
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Calculation of PNEC water was based on the result obtained in long-term study on Daphnia Magna reporting a NOEC > 10 mg/l. Assessment factors of 100 and 1000 were used for fresh water and marine water, respectively.
The derivation of PNEC water (intermittent releases) was done by applying an assessment factor of 100 to the lowest value obtained in at least three short-term aquatic toxicity studies from three trophic levels. Accordingly, a concentration of 100 mg/l was used. For marine water (intermittent release) the AF used is 1000.
The value of PNEC STP was derived from the result of the activated sludge respiration inhibition test EC50 = 1000 mg/l by using an assessment factor of 100.
Due to the lack of ecotoxicological data, PNEC sediment for fresh water and marine water were calculated using equilibrium partitioning method. This method uses PNEC water for aquatic organisms and suspended matter/water partition coefficients as inputs. Note that this approach is used only as a rough screening since it may result in both an overestimation or underestimation of toxicity.
The amount of test substance in the air compartment was expected to be very low, since the substance is a solid with a negligible vapour pressure. Therefore, no hazard was identified.
The calculation of PNEC soil was done using the assessment factor method. The only data available is coming from a test on eisenia fetida for which a NOEC value is reported. The test follows OECD 207 thus the NOEC is better considered as an EC50 (acute toxicity value). The value obtained is EC50 > 1000 g/kg soil dw, thus the corresponding assessment factor is 1000.
Secondary poisoning concerns toxic effects in the higher members of the food chain which results from ingestion of organisms from lower trophic levels that contain accumulated substances is relevant for highly lipophilic organic chemicals, with a log Kow above the cutoff value of 4 reported in the CLP Regulation (EC 1272/2008). Due to the absence of potential for bioaccumulation indicated by a log Kow = - 3.0, test substance was considered as not hazardous with respect to secondary poisoning.
Conclusion on classification
According to the CLP Regulation (EC n. 1272/2008), Part 4: Environmental Hazards, the substances can be classified for hazardous to the aquatic environment when the following criteria are met:
A) Acute (short-term) aquatic hazard
Category Acute 1: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) ≤ 1 mg/l;
B) Long-term aquatic hazard
(i) Non-rapidly degradable substances for which there are adequate chronic toxicity data available:
Category Chronic 1: Chronic NOEC or ECx(for fish and/or for crustacea and/or for algae or other aquatic plants) ≤ 0.1 mg/L,
Category Chronic2: Chronic NOEC or ECx(for fish and/or for crustacea and/or for algae or other aquatic plants)> 0.1 to ≤ 1 mg/L;
The substance was tested in acute tests with fish, Daphnia and Lemna Gibba. No effects occurred and the LC50/EC50s were determined to be > 100 mg/L. Furthermore, chronic values are available for Daphnia Magna. The NOEC was determined to be > 10 mg/L and the substance is non-rapidly degradable.
In conclusion the substance is not classified for the water compartment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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