1-hydroxy-4-(p-toluidino)anthraquinone

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

according to guideline

Guideline:

other: Measurements of Octanol and Water solubility of Pigments (2006), carried out by ETAD Member companies. Data ownership is with ETAD.

Version / remarks:

January 12, 2005

Deviations:

no

Principles of method if other than guideline:

WATER
About 5 mg of the test sample were suspended in 30 ml water (bi dest.) in a sample flask (standard flask for the Büchi Rack R-24, volume 30 ml (Art.-No. 038469)) and were shaken for two hours at 30°C (+/- 2°C) on a “Büchi Syncore Polyvap” (laboratory shaking machine) with 400 rpm. Then shaking was continued at ambient temperature (24 – 25°C) for 70 hours, followed by filtration through a 0.05 μm membrane filter (Fa. Schleicher und Schuell, NC 05, Ref.-No.: 402110) (on the filter there remained a residue of not dissolved colorant).
The resulting clear solution was measured by UV-vis spectrometry and the absorption was determined at 583 nm. The concentration of the sample could be determined by applying the Lambert-Beer rule. A calibration curve of Solvent Violet 13 in DMSO (Merck, für die Spektroskopie “Uvasol”, Bestell-Nr.: 1.02950.2500) was used for that purpose.
The determination was repeated for three times.

OCTANOL
About 20 mg of the test sample were suspended in 30 ml octanol (Aldrich, spectrophotometric grade) in a sample flask (standard flask for the Büchi Rack R-24, volume 30 ml (Art.-No. 038469)) and were shaken for two hours at 30°C (+/- 2°C) on a “Büchi Syncore Polyvap” (laboratory shaking machine) with 400 rpm. Then shaking was continued at ambient temperature (24 – 25°C) for 70 hours, followed by filtration through a 0.2 μm membrane filter (Fa. Schleicher und Schuell, TE 35, Ref.-No.: 411411) and then through two 0.2 μm membrane filters (Fa. Schleicher und Schuell, TE 35, Ref.-No.: 411411) (on the filter there remained a residue of not dissolved colorant).
The resulting clear solution was measured by UV-vis spectrometry and the absorption was deter-mined at 585 nm. The concentration of the sample could be determined by applying the Lam-bert-Beer rule. A calibration curve of Solvent Violet 13 in DMSO (Merck, für die Spektroskopie “Uvasol”, Bestell-Nr.: 1.02950.2500) was used for that purpose.
The determination was repeated for three times.

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

- Purity: 100 % (pure)
- Trade name: Solvent Violet 13
- Batch No.: 0832B
- CLAS Order No: 06-06078

Water solubility:

0.009 mg/L

Temp.:

25 °C

Remarks on result:

other: no pH-value reported

Details on results:

Based on the calibration curve of the test item in DMSO (Merck, "Uvasol”, Order-No.: 1.02950.2500) the concentration of the sample was determined by applying the Lambert-Beer rule.

Individual results:

Water

	Absorption (d = 10 cm)	µg/L
a1	0.001719	10.1
a2	0.002142	11.3
a3	0.000401	6.6

Octanol

	Absorption (d = 10 cm, dilution 1:50)	g/L
a1	0.1245	0.17
a2	0.1269	0.17
a3	0.1349	0.18

Conclusions:

For Solvent Violet 13 the water solubility of 0.0093 mg/L was obtained in demineralized water at ambient temperature (24-25°C) and no pH-value was reported.

Executive summary:

The determination of the water solubility of Solvent Violet 13 by the flask method was based on the "Measurements of Octanol and Water solubility of Pigments" (ETAD, 2006). The solution was measured by UV-Vis spectrometry and the absorption was determined at 583 nm and the concentration of the sample could be determined by applying the Lambert-Beer rule. For Solvent Violet B the water solubility of 0.0093 mg/L (mean value) was obtained in demineralized water at ambient temperature (24 -25 °C) and no pH-value was reported.

Description of key information

The water solubility of 0.0093 mg/L was obtained in demineralized water at ambient temperature (24-25°C) and no pH-value was reported.

Key value for chemical safety assessment

Water solubility:

0.009 mg/L

at the temperature of:

25 °C