Bis(5-oxo-L-prolinato-N1,O2)copper

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Remarks:

non-guideline and non-specific method, acceptable for highly soluble substances

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

In a glass reaction vessel, introduce 1 litre of demineralised water and the pidolic acid salt respectively, until a saturated solution is obtained. The reagent vessel is then constantly stirred. The temperature of the mixture is heated to 80°C for 3 hours in order to ensure that the solution is saturated with pidolic acid salt.

The stirring process is subsequently stopped to allow the insoluble part of the pidolic acid salt to form sediment and, after 15 minutes of sedimentation, a sample is collected from the upper phase and tested. The sample, thus obtained is diluted to ½ in order to avoid parasite crystallisation of the product.

The reagent is then replaced with stirring and the temperature is adjusted as required. Once the temperature is reached, the mixture ismaintained at this temperature for 1 hour before collecting a new sample according to the afore-mentioned procedure.
This procedure was carried out at 20°C; 30°C, 40°C, 50°C, 60°C, 70°C and 80°C.

The concentration of the solution is determined by measuring the dry matter obtained at 115°C for 15 hours.

GLP compliance:

no

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

Bis(5-oxo-L-prolinato-N1,O2)copper

EC Number:

239-471-4

EC Name:

Bis(5-oxo-L-prolinato-N1,O2)copper

Cas Number:

15454-74-7

Molecular formula:

C10H12CuN2O6

IUPAC Name:

bis(5-oxo-L-prolinato-N1,O2)copper

Results and discussion

Water solubility

Key result

Water solubility:

132 g/L

Temp.:

20 °C

Remarks on result:

other: pH not provided

Applicant's summary and conclusion

Conclusions:

The water solubility of the test item is 132 g/L at 20°C.