Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 257-775-5 | CAS number: 52238-69-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Adequate chronic toxicity data is not available for Direct Yellow 142, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available on the substance and on the structural analogues.
Direct Yellow 142 is very water soluble and it is not rapidly degradable. It has a log Kow lower than 4, indicating a low potential for bioaccumulation; in addition, on the basis of the molecular mass greater than 700, it is expected to be not readily taken up by fish, because of possible steric hindrance at passage of gill membranes or cell membranes of respiratory organs.
Key outcomes concerning the tests run on organisms belonging to the aquatic compartment:
- no effects or mortality were observed during the short-term toxicity test on fish (Cyprinus carpio) up to the limit concentration of 1000 mg/l (nominal)
- no immobilized invertebrates (Daphnia magna) were observed during the 48 -hours test; thus, the 48-h NOEC to Daphnia magna was determined to be at least 78 mg test item/l and EC50 48-h is likely to be higher than 100 mg test item/l
- for toxicity to aquatic plants (Lemna minor), the ErC50 (7d) resulted to be greater than the highest tested concentration of 100 mg/l (meas. geom mean)
- after 3 hours of exposure, no inhibition of microorganisms was recorded up to the highest concentration tested of 1000 mg/l
No acute toxicity (i.e. L(E)C50) was recorded in none of the experiments conducted on fish, invertebrate and aquatic plant, up to the higher concentration reached in the tests; therefore, the PNEC vales have been estimated using the lowest tested value.
The test substance resulted to be no harmful-toxic for activated sludge and not negatively impacting the microorganism activity; thus, it is deemed to be not able to affect the sewage treatment plants systems function.
Direct releases to air and/or sediment and/or soil are considered to be not relevant, on the basis of the substance usages describe into the IUCLID section 3.3; in addition, the physicochemical properties support the expectation of low relevance of the mentioned compartments.
The primary source of possible substance environmental release is represented by industrial waste waters.
Conclusion on classification
Adequate chronic toxicity data is not available for Direct Yellow 142, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available on the substance and on the structural analogues.
Direct Yellow 142 is very water soluble and it is not rapidly degradable; on the basis of the chemical structure characteristics and the negative log Kow (i.e. -3.31 at 20 °C), the substance is expected to be possess a low potential for bioaccumulation.
No L(E)C50 value was recorded at concentration equal/lower than 1 mg/l, thus the classification criteria for acute (short-term) aquatic hazard (category 1) of the CLP Regulation (EC) No 1272/2008 are not met.
In addition, no acute toxicity (i.e. L(E)C50) was recorded in none of the experiments conducted, up to the concentration of 100 mg/l; thus the classification criteria for long-term aquatic hazard (categories 2/3/4) of the CLP Regulation (EC) No 1272/2008 are not met.
In conclusion, the outcomes of the tests performed suggest that Direct Yellow 142 is not harmful/toxic for aquatic life.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.