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Diss Factsheets
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EC number: 233-437-2 | CAS number: 10168-81-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_toxicological-information.png)
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- determination of pH value and acid reserve
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
- Principles of method if other than guideline:
- Electrochemical determination of pH value and determination of acid reserve via titration.
- GLP compliance:
- no
- Remarks:
- not required for this type of test
Test material
- Reference substance name:
- Gadolinium trinitrate
- EC Number:
- 233-437-2
- EC Name:
- Gadolinium trinitrate
- Cas Number:
- 10168-81-7
- Molecular formula:
- Gd(NO3)3
- IUPAC Name:
- gadolinium trinitrate
- Details on test material:
- No information on test material.
Constituent 1
Test animals
- Species:
- other: not applicable
- Strain:
- other: not applicable
- Details on test animals or test system and environmental conditions:
- not applicable
Test system
- Type of coverage:
- other: not applicable
- Preparation of test site:
- other: not applicable
- Vehicle:
- other: not applicable
- Details on study design:
- pH-value determination:
The pH-value of a 10% solution (or slurry) is determined electrochemically at 20 °C with a calibrated pH meter (MA 235 Mettler Toledo).
Determination of acid reserve titration:
- For the determination of the acid reserve: the titration volume (in mL) of a 1 mol/L NaOH solution, which is required to achieve a pH of 4 of a 10% solution (or slurry) at 20 °C, is recorded.
Calculations:
- Titration of the 10% solution/slurry
- Acid reserve = titration volume (mL) x 0.4
Criterion for corrosivity: a product is classified as corrosive if: pH - 1/12 acid reserve <= -0.5
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- other: pH
- Score:
- 2.7
- Remarks on result:
- other: Based on the results of a pH/acid reserve determination, the substance is considered not to be corrosive. pH was 2.7 and acid reserve 0.05. Corrosivity calculation = 2.7.
- Irritation parameter:
- other: acid reserve
- Score:
- 0.05
- Remarks on result:
- other: Based on the results of a pH/acid reserve determination, the substance is considered not to be corrosive. pH was 2.7 and acid reserve 0.05. Corrosivity calculation = 2.7.
- Irritation parameter:
- other: corrosivity calculation
- Score:
- 2.7
- Remarks on result:
- other: Based on the results of a pH/acid reserve determination, the substance is considered not to be corrosive. pH was 2.7 and acid reserve 0.05. Corrosivity calculation = 2.7.
- Irritant / corrosive response data:
- not corrosive
Applicant's summary and conclusion
- Interpretation of results:
- other: not corrosive following CLP guidance
- Conclusions:
- The pH value of a 10% solution of gadolinium trinitrate was determined to be 2.7 and the acid reserve was 0.05. Based on these data, the calculation for corrosivity was 2.7. Therefore the substance was considered not to be corrosive.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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