Registration Dossier
Registration Dossier
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EC number: 258-771-6 | CAS number: 53786-28-0
Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosive properties of explosives
- Type of information:
- other: Expert statement
- Adequacy of study:
- supporting study
- Study period:
- 27 July - 02 December 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Expert statement following no specific guideline and without detailed description of results.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Expert statement.
- GLP compliance:
- no
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- It is concluded that the substance T000990 does not have explosive properties.
- Endpoint:
- explosive properties of explosives
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
Referenceopen allclose all
None of the components of the test item does contain chemical groups which are associated with explosive properties. The molecular structures of any impurities =<1% were not taken into account. In conclusion, JNJ-119743-AAA (T000990) has no explosive properties.
Description of key information
Based on an expert statement (Brekelmans, 2016), T000990 is considered not to contain any chemical groups indicative of explosive properties. Further testing was not required and T000990 is concluded not to have explosive properties.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
A study of which the reliability was not assignable (K4, Janssen Pharmaceutica Process Safety Center, 1985) concluded that the test substance is not shock sensitive (sensitivity > 39.2 Nm) (Lütolf method). This study supports the conclusions of the expert statement.
Justification for classification or non-classification
T000990 does not need to be classified as explosive as based on the chemical structure T000990 does not contain any chemically instable or highly energetic groups that might lead to an explosion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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