Registration Dossier
Registration Dossier
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EC number: 819-930-0 | CAS number: 37288-51-0
Endpoint summary
Administrative data
Description of key information
Licheninase was tested for acute toxicity to crustacean and algae. These were however supporting studies. Other cross-reference studies were included with alpha-amylase (IUB 3.2.1.1), belonging to the same class of enzymes.
For crustacean Daphnia magna: Under the conditions of the test, licheninase, batch PPB41588 was not found to be toxic to Daphnia magna at a nominal concentration up to 100 mg TOS/L after 48h exposure. Thus, no 48h EC50 could be calculated and must be >100 mg TOS/L (>6.42 mg/L aep). The 48h EC50 value for alpha-amylase with Daphnia magna was 2000 mg test material/L corresponding to 212 mg active enzyme protein/L.
For algae: Licheninase batch PPB41588 was not toxic to Pseudokirchneriella subcapitata as no significant growth inhibition was observed up to a concentration of 100 mg TOS/L. Thus, no 72h ErC50 could be calculated, and should be >100 mg TOS/L (>6.42 mg/L aep). Alpha-amylase is inhibitory to the growth of Desmodesmus subspicatus at concentrations in excess of 12.5 mg/L corresponding to 1.3 mg active enzyme protein (aep)/mL. The EbC50 (72h) value is 24 mg/L and the ErC50 (24-72h) is 49 mg/L corresponding to 2.5 and 5.2 mg aep/L, respectively.
Additional information
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