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EC number: 500-039-8 | CAS number: 25322-69-4 1 - 4.5 moles propoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
An assessment of the PBT status of ‘propane-1,2-diol, propoxylated’ has been made using all available data. The information available suggests that the substance does not meet the PBT screening criteria as outlined in Annex XIII of Directive 2006/121/EC. Detailed analysis of each of the main components listed in chapter 1.2 of the IUCLID dossier are shown in the individual entries in this chapter. A summary of the PBT assessment is shown below.
Persistence
Manometric Respirometry tests (OECD 301F) showed that the structural analogues and constituents mono-, di and tripropylene glycol are ready biodegradable and that the higher order analogues tetra and pentapropylene glycol are inherently biodegradable. Therefore, polypropylene glycol can be regarded as biodegradable and thus not persistent.
Bioaccumulation
Based on the result of the octanol/water partition coefficient (log Kow of < 0.3 - 1.13), it is expected that ‘propane-1,2-diol, propoxylated’ has no bioaccumulative potential.
Toxicity
Experimental data on acute toxicity are available for the structural analogies and constituents di- and tripropylene glycol. All acute L(E) C50values are much higher than the screening criterion of 0.1 mg/l. ‘Propane-1,2-diol, propoxylated’ is not classified as being a CMR substance and there is no evidence that it is chronically toxic towards mammals. It can therefore be expected that ‘propane-1,2-diol, propoxylated’ is not toxic towards aquatic organisms
- Likely routes of exposure:
‘Propane-1,2-diol, propoxylated’ is not a PBT/vPvB substance, therefore the emission characterisation need not to be conducted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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