Registration Dossier
Registration Dossier
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EC number: 203-628-5 | CAS number: 108-90-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- CLH report for Chlorobenzene. Proposal for Harmonised Classification and Labelling
- Year:
- 2 013
- Bibliographic source:
- CLH report. Proposal for Harmonised Classification and Labelling.
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- GLP compliance:
- not specified
- Remarks:
- not specified
- Test type:
- other: not specified
Test material
- Reference substance name:
- Chlorobenzene
- EC Number:
- 203-628-5
- EC Name:
- Chlorobenzene
- Cas Number:
- 108-90-7
- Molecular formula:
- C6H5Cl
- IUPAC Name:
- chlorobenzene
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 15.5 mg/L air
- Exp. duration:
- 4 h
- Remarks on result:
- other: omparable study with OECD 403
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 16.1 mg/L air
- Exp. duration:
- 4 h
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 29.6 mg/L air
- Exp. duration:
- 4 h
- Remarks on result:
- other: OECD 403
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- The intermediate is classified as harmful if inhaled (CLP Regulation - category 4)
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