Registration Dossier
Registration Dossier
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EC number: 942-589-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Eye irritation, Eye Irritection assay, H318: Causes serious eye damage
Skin irritation, Dermal Irritection assay, slight irritant. Overall assessment: not skin irritant
Key value for chemical safety assessment
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irreversible damage)
Additional information
In vitro Irritection tests are available for both eye and skin irritation properties (Ricci; 2002) on the substance and on a group of substances that differ from the target substance only for the lenght of the fatty acid in the final structure.
Eye irritation was determined by Ocular Irritection Assay on the substance (and similar substances) with a result as a mild/modearte eye irritant in the Draize score system.
Skin irritation was determined on the substance by Dermal Irritection Assay, which resulted as mild skin irritant. However, based on the considerations reported in the attached document and on the read across considerations no skin irritation potential is considered for the substance while eye irritation potential is classified as H318.
Effect level: empty Endpoint conclusion: Adverse
effect observed
Justification for classification or non-classification
The irritative scores determined by the Irritection Assay (dermal and Ocular) classify the substance as H318 and do not classify the substance for skin irritation under Regulation 1272/2008 ( refer to the attached document).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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