Norethisterone

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

other: UN test procedure "Recommendations on the Transport of Dangerous Goods - Manual of Tests and Criteria" (UN-MTC), Part III, sub-section 33.2.1.4.1, Test N.1 "Test method for readily combustible solids"

Deviations:

no

GLP compliance:

no

Key result

Test procedure:

burning rate test with wetted zone

Burning time:

<= 2 min

Remarks on result:

other:

Remarks:

The test substance melted when approached by the ignition flame. The substance did not burn up.

The substance in its delivery state was measured. The test substance melted when approached by the ignition flame. The substance did not burn up. No further testing was required.

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

17-ethynyl-17-hydroxyestr-4-en-3-one is in the sense of the CLP-Guideline a non-flammable solid.

Executive summary:

17-ethynyl-17-hydroxyestr-4-en-3-one in its delivery state was measured. The test substance melted when approached by the ignition flame. The substance did not burn up. No further testing was required. 17-ethynyl-17-hydroxyestr-4-en-3-one is classified as a not readily combustible solid when tested according to UN-MTC Procedure N.1.

Reference 2

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the organic substance does not contain metals or metalloids and hence, the classification procedure does not need to be applied

Reference 3

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Reference 4

Endpoint:

self-heating substances / mixtures

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Description of key information

a.) Flammability: 17-ethynyl-17-hydroxyestr-4-en-3-one is no flammable solid according to UN-MTC Procedure N.1.

b.) Pyrophoric properties: 17-ethynyl-17-hydroxyestr-4-en-3-one did not deliver indications of pyrophoric properties during the realization of other tests. The determination according to UN-MTC Procedure N.2 is not necessary.

c.) Contact with water: A review of the structure suggests that there are no chemical groups present that would imply pyrophoric properties or flammability on contact with water. A review of handling and used implies no pyrophoric properties or flammability on contact with water. Testing according to UN Procedure N.5 is not necessary.

d.) Self-heating substances: Based on the thermal behavior according to EC A.16 (no safety-relevant exothermic reactions were detected) it is expected that 17-ethynyl-17-hydroxyestr-4-en-3-one is not a self-heating substance. 17-ethynyl-17-hydroxyestr-4-en-3-one can be classified as a not self-heating substance in the sense of CLP Annex 1, 2.11.

Key value for chemical safety assessment

Flammability:

not classified