Registration Dossier
Registration Dossier
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EC number: 201-714-7 | CAS number: 86-98-6
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
The pseudo first order hydrolysis rate constant of test chemical was determined to be < 0.9 m/hr with a corresponding half-lives off > 879 years at pH 7 and a temperature of 25°C, respectively.
The half-life period of test chemical was determined to be 75 days at pH 4 and thus test chemical was reported to be hydrolytically stable at pH 7 and 9.
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be ranges from 75 days to >879 yr, at pH range 4 and 7, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is expected to be stable in water.
Additional information
Hydrolysis:
Data available for the test chemical and structually and functionally similar read across chemicals has been reviewed to determine the half-life of hydrolysis as a function of pH. The studies are as mentioned below:
The half-life of the test chemical was determined at different. The study was performed at pH 7 & at a temperature of 25°C, respectively. The pseudo first order hydrolysis rate constant of test chemical was determined to be < 0.9 m/hr with a corresponding half-lives of >879 years at pH 7 and a temperature of 25°C, respectively. Based on the half-life values, it is concluded that the chemical was not hydrolysable.
Above study further supported by the third weight of evidence study from authoritative database. The half-life of the test chemical was determined at different pH range. The study was performed at pH of 4, 7 and 9. The half-life period of test chemical was determined to be 75 days at pH 4 and thus test chemical was reported to be hydrolytically stable at pH 7 and 9. On the basis of this, test chemical was considered to be not hydrolysable.
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical can be expected to be ranges from 75 days to >879 yr, at pH range 4 and 7, respectively. Thus, based on this half-life value, it can be concluded that the test chemical is expected to be stable in water.
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