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EC number: 207-997-3 | CAS number: 504-63-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The test substance (CAS No. 504-63-2) is liquid with a freezing point of -24.6ºC and a boiling point of 208.9ºC using ASTM D1120-94 2004.
In accordance with REACH Annex VII, the density of 1,3-propanediol was measured relative to water to give a relative density of 1.05 at 25°C using USP <841> Method 1. The vapour pressure was determined to be 3.91 Pa at 25°C (calculated using MPBPVP v. 1.43). The log Kow is -0.71 at 25°C (calculated using KOWWIN v. 1.67). Supporting documentation for these calculations is documented using the QSAR Prediction Reporting Format (QPRF) version 1.1, May 2008 and the Q(SAR) model is documented in a QMRF. The surface tension is 74.161 mN/m. The water solubility is >1000 g/L in distilled water.
In accordance with REACH Annex VII, the flash point was measured and determined to be > 99°C using method ASTM Method D56 (Tag Closed Cup). In accordance with section 1 of REACH Annex XI, information requirement section 7.10, a flammability study does not need to be conducted because for liquids the primary value for ease of ignition is the flash point. According to ECHA Chapter 7 guidance the flammability is deduced from flash point. The test substance is classified as a Class IIIB combustible liquid due to a flash point greater than 93.4°C. In accordance with Section 2 of REACH Annex XI, information requirement section 7.10, additional flammability studies do not need to be conducted because based on chemical structure pyrophoricity or water reactivity is not to be expected. According to ECHA Chapter 7 guidance, experience in handling and use provides sufficient information to indicate that this substance is not pyrophoric or water reactive.
In accordance with Column 2 adaptation statement of REACH Annex VII, information requirement section 7.11 explosivity testing does not need to be conducted based on a structural assessment of the substance. Examination of the structure indicates that there are no groups associated with explosive properties. Therefore, negative results can be predicted and no testing for explosive properties has been carried out. The self-ignition temperature is 342°C as determined by ASTM Method E659-78 (Reapproved 2005). In accordance with Column 2 adaptation statement of REACH Annex VII, information requirement section 7.13, a study on oxidising properties does not need to be conducted based on structural assessment of the substance. The test substance contains no oxidising groups and all oxygen atoms are bonded directly to carbon atoms. In accordance with Column 2 adaptation statement of REACH Annex VII, information requirement section 7.14, granulometry does not need to be conducted for liquids or gases. In accordance with Column 2 adaptation statement of REACH Annex IX, information requirement section 7.15, the stability in organic solvents does not need to be assessed since it is not considered critical. This would be assessed in individual studies where organic solvents are used. In accordance with Section 2 of REACH Annex XI, information requirement section 7.16,a dissociation study does not need to be conducted as the test substance has no dissociable groups. According to ECHA Chapter 7 guidance, measurement of pKa is irrelevant as the substance cannot dissociate due to a lack of relevant functional groups. The viscosity of the test substance is 44.923 mm2/s (cSt) at 24°C.
For details on references see the IUCLID dataset.
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