Beryllium oxide

Particle size distribution (Granulometry)

Administrative data

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: - study conducted in general accordance to OECD 110

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)

GLP compliance:

no

Type of distribution:

volumetric distribution

Test material

Test material information

Constituent 1

Reference substance name:

Beryllium oxide

EC Number:

215-133-1

EC Name:

Beryllium oxide

Cas Number:

1304-56-9

Molecular formula:

BeO

IUPAC Name:

oxoberyllium

Details on test material:

- Name of test material (as cited in study report): beryllium oxide
- Substance type: metal oxide
- Physical state: solid, powder
- Analytical purity: 99.9
- Impurities (identity and concentrations): not reported
- Purity test date: not reported
- Lot/batch No.: UOX LOT NO. 1846-B
- Expiration date of the lot/batch: not reported, but irrelevant due the stability of the metal oxide
- Stability under test conditions: not reported, but generally known to be very stable

Results and discussion

Particle size

Percentile:

D50

Mean:

1.331 µm

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

Any other information on results incl. tables

- Table 1: Particle Size Distribution of UOX LOT NO. 1846-B

Size (µm)	%Pass
9.250	99.59
7.778	98.98
6.641	98.07
5.500	96.73
4.625	94.79
3.889	92.03
3.270	88.23
2.750	83.29
2.312	77.24
1.845	70.14
1.635	61.85
1.376	52.04
1.158	40.87
0.972	29.6
0.818	19.68
0.688	12.19
0.578	6.81
0.486	3.35
0.409	1.24
0.344	0.33
0.289	0.00
0.243	0.00
0.204	0.00
0.172	0.00
0.145	0.00

for graphical representation please refer to the attached figure

Applicant's summary and conclusion

Conclusions:

In conclusion, using the laser diffraction method to study the particle size of Lot 1846-B ranging between 0.04 µm and 704 µm, the mass median diameter (MMD) was determined to be 1.331 µm.
The particle size distribution was found to range from approximately 0.3 µm to 10 µm.

Executive summary:

In the present study (Sayer 2010) the particle size distribution of beryllium oxide (sample: UOX Lot 1846 -B) was tested using the laser differaction method.

The mass median diameter (MMD) was determined to be 1.331 µm and the particle size distribution was found to range from approximately 0.3 µm to 10 µm.

The test item was measured in dispersion (deionized water with a surfactant, sonificated) at room temperature using a Microtrac® X100 (Particle size range: 0.04 µm to 704 µm, standard program) and the final value derived as average of 3 measurements. A check sample with a known particle size distribution is tested before and after analysis. The percentile distribution and mean volume results are compared with the known check sample values to verify test equipment accuracy.

Brush Wellman’s laboratory performed this analysis and is ISO 17205 certified.