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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
data is from experimental reports
Reference:
Composition 1
Qualifier:
according to
Guideline:
other: as mentioned below
Principles of method if other than guideline:
The particle size distribution of 4-acetamido-5-[[4-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]anthranilic acid, sodium salt was determined by granulometric analysis with rotap sieve shaker.
GLP compliance:
not specified
Type of method:
sieving
Type of particle tested:
primary particle
Type of distribution:
counted distribution
Test material information:
Composition 1
Specific details on test material used for the study:
- Name of test material: 4-acetamido-5-[[4-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]anthranilic acid, sodium salt
- IUPAC name: 2-amino-4-acetamido-5-[(E)-2-(4-{[2-(sulfooxy)ethane]sulfonyl}phenyl)diazen-1-yl]benzoic acid sodium
- Molecular formula: C16H18N4O10S3.x-Na
- Molecular weight: 566.4984 g/mole
- Smiles:S(=O)(=O)(c1cc(c(cc1N)NC(=O)C)/N=N/c1ccc(S(=O)(=O)CCOS(=O)(=O)[O-])cc1)[O-].[Na+].[Na+]
- Inchl: 1S/C16H18N4O10S3.2Na/c1-10(21)18-14-8-13(17)16(32(24,25)26)9-15(14)20-19-11-2-4-12(5-3-11)31(22,23)7-6-30-33(27,28)29;;/h2-5,8-9H,6-7,17H2,1H3,(H,18,21)(H,24,25,26)(H,27,28,29);;/q;2*+1/p-2/b20-19+;;
- Substance type: Organic
- Physical state: Solid powder
Key result
Percentile:
D50
Remarks on result:
other: mass median diameter
No.:
#1
Size:
146 µm
Distribution:
11.11 %
Remarks on result:
other: no other details mentioned
No.:
#2
Size:
103 µm
Distribution:
45.65 %
Remarks on result:
other: no other details mentioned
No.:
#3
Size:
72.31 µm
Distribution:
20.02 %
Remarks on result:
other: no other details mentioned
No.:
#4
Size:
51 µm
Distribution:
16.1 %
Remarks on result:
other: no other details mentioned
Conclusions:
The particle size distribution of 4-acetamido-5-[[4-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]anthranilic acid, sodium salt was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 146 micron to 51 micron.
Executive summary:

The particle size distribution of 4-acetamido-5-[[4-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]anthranilic acid, sodium salt was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 146 micron to 51 micron.

Description of key information

The particle size distribution of 4-acetamido-5-[[4-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]anthranilic acid, sodium salt was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 146 micron to 51 micron.

Additional information

The particle size distribution of 4-acetamido-5-[[4-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]anthranilic acid, sodium salt was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determined to be in the range of 146 micron to 51 micron.