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EC number: 272-812-5 | CAS number: 68915-39-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guidelien study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Ethyl difluoroacetate
- EC Number:
- 207-223-4
- EC Name:
- Ethyl difluoroacetate
- Cas Number:
- 454-31-9
- IUPAC Name:
- ethyl difluoroacetate
- Reference substance name:
- 5-Ethylpyridine-2,3-dicarboxylic Acid
- IUPAC Name:
- 5-Ethylpyridine-2,3-dicarboxylic Acid
- Details on test material:
- - Name of test substance: Natriumcarboxylat- Lösung
- Test substance No.: 09/0194-1
- Batch identification: Probe EX 1672 vom 16.03.2009
- CAS No.: 68915-39-9
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Composition:
Hydroxycapronic acid 4.1 %(weight)
Valerianic acid 7.4 %(weight)
Glutaric acid 0.49 %(weight)
Capronic acid 3.3 %(weight)
Adipic acid 2.5 %(weight)
Formic acid 2.4 %(weight)
Acetic acid 1.3 %(weight)
Succinic acid 0.17 %(weight)
Propionic acid 0.45 %(weight)
Butyric acid 1.1 %(weight)
Water 53.6 %(weight)
Sodium carbonate 1.65 %(weight)
Sodium hydrogencarbonate 2.47 %(weight)
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
- Details on test solutions:
- - The test solution was prepared by dissolvation of 259.69 mg in 1L M4-medium.
- The test solution was stirred for about 10 minutes at 20 ± 2 °C to ensure complete dissolvation.
- the test solution was visibly clear and colored light yellow
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna STRAUSS
- Source: Daphnia magna Straus was originally supplied from "Institut National de Recherche Chimique appliquee, France", and has been breeded from 1978 in the Laboratories of BASF.
- Age at study initiation (mean and range, SD): 2 - 24 hours old
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 2.20 - 3.20 mmol/L
- Test temperature:
- 19.8 - 21.5 °C
- pH:
- 8.1 - 8.7
- Dissolved oxygen:
- 8.2 - 9.2
- Nominal and measured concentrations:
- Nominal: 0 and 260 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type (delete if not applicable):closed
- Material, size, headspace, fill volume: 20 ml glass tubes with flat bottom, 10 ml test volume
- Aeration:
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: M4 medium with the properties:
Total hardness: 2.20 - 3.20 mmol/L
Alkalinity up to pH 4.3: 0.8 - 1.0 mmol/L
Ratio Ca/Mg ions: about 4:1
pH value: 7.5 - 8.5
Conductivity: 550 - 650 microS/cm
OTHER TEST CONDITIONS
- Photoperiod: 16:8 hours, diffuse light (about 2-7 microeinstein/m*m*s (400-750 nm))
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Observations: mobile daphnids after 24 and 48 h
Measurements: Temperature, pH and oxygen content after 0 and 48 h - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 115 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: adjusted to water content
- Basis for effect:
- mobility
- Remarks on result:
- other: 248 mg/L non-adjusted t owater content adjusted to a water content of 53.6%
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 248 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: non-adjusted to water content
- Basis for effect:
- mobility
- Remarks on result:
- other: Test substance incl. 53.6% /weight (water)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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