Benzyl isovalerate

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-01-13 – 2017-01-13

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental result performed using standard methods of analysis

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Principles of method if other than guideline:

The density of test chemical was determined following OECD guideline 109 and according to the Indian standard method for determination of density of liquids.

GLP compliance:

no

Type of method:

pycnometer method

Key result

Type:

density

Density:

1.057 g/cm³

Temp.:

20 °C

By Pyknometer Method:

Method Details		Observed Values
		1st Observation	2nd Observation
Guideline	OECD 109
Method	IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision)
Principle of Method	Determination of the mass at a given temperature of a volume of the material contained in a density bottle (pyknometer) and determination of the volume of the latter by determining the mass of the corresponding volume of water at the same temperature. The density is obtained by dividing the mass of material by its volume.
Test temperature	(°C)	20 °C	20.0°C
Atmospheric pressure	(hPa)	976.5	976.4
Weight of empty dry pyknometer(X)	g	29.281	29.379
Weight of pyknometer + test item (Y)	g	82.067	81.722
Apparent mass of test item (M1)	(M1 = Y - X) g	52.786	52.343
Weight of pyknometer + water (Z)	g	78.977	80.906
Apparent mass of water (M2)	(M2 = Z - X) g	49.696	49.509
Buoyancy correction (A)	A = (*ρat × M2)	0.058	0.057
(WA-WB)	g/cm³ (ρtw)	0.9982	0.9982

 

CALCULATIONS:

Density = (M1+A)/ (M2+A) X ρtw

1st calculated density	2nd calculated density
(52.786+0.058) ____________ X 0.9982 = 1.060 g/cm3 g/cm³ (49.696+0.058)	(52.343+0.057) ____________ X 0.9980 = 1.055 g/cm3 g/cm³ (49.509+0.057)
Average density	= 1.057 g/cm³

 

Conclusions:

The density of test chemical was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test chemical was determined to be1.057 g/cm³ at 20°C and 976.4 hPa.

Executive summary:

The density of test chemical was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test chemical was determined  to be1.057 g/cm³ at 20°C and 976.4 hPa.

Description of key information

The density of test item was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test item was determined  to be1.057 g/cm³ at 20°C and 976.4 hPa.

Key value for chemical safety assessment

Relative density at 20C:

1.057

Additional information

The density of test item was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test item was determined  to be1.057 g/cm³ at 20°C and 976.4 hPa.

Other supporting studies from reliable sources such as review article and handbooks suggests that the density of chemical was reported to be in the range of 0.981 g/cm3 to 0.9983 g/cm3.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of density as 1.057 g/cm³ at 20 degree C ,thus considered as key study for the chemical safety assessment.