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EC number: 941-981-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Data on the aquatic toxicity of Fatty acids, C18 unsaturated,
ethyl & methyl esters (EC 941-981-3) are only available for fish and
aquatic invertebrates.
In accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006,
read-across to the structurally related substances Fatty acids, C16-18
and C18-unsatd., iso-Bu esters (CAS 84988-79-4) and Fatty acids,
safflower-oil, ethyl esters (CAS 91051-53-5) was conducted to fulfil the
standard information requirements. In accordance with Article 13 (1) of
Regulation (EC) No 1907/2006, "information on intrinsic properties of
substances may be generated by means other than tests, provided that the
conditions set out in Annex XI are met.” In particular for aquatic
toxicity, information shall be generated whenever possible by means
other than vertebrate animal tests, which includes the use of
information from structurally related substances (grouping or
read-across). According to Annex XI, Item 1.5, of Regulation (EC) No
1907/2006 substances can be considered to be similar if their
physicochemical, toxicological and ecotoxicological properties are
likely to be similar or follow a regular pattern as a result of
structural similarity.
Fatty acids, C18 unsaturated, ethyl & methyl esters (EC 941-981-3)
is an UVCB substance consisting of ethanol and methanol esterified with
poly- and monounsaturated C18 fatty acids. The source substance Fatty
acids, safflower-oil, ethyl esters (CAS 91051-53-5) consists of ethanol
esterified with a linear, poly-unsaturated fatty acid chain with two
double bonds. The source substance Fatty acids, C16-18 and C18-unsatd.,
iso-Bu esters (CAS 84988-79-4) is an UVCB substance comprising linear
saturated and unsatured fatty acid chains (C14 – C18) esterified with a
linear C4 alcohole. The read across substances cover the chain length as
well as the characteristics of saturated and unsatured fatty acid chains
of the source substance. Target and source substances are characterised
by a low water solubility, low vapour pressure and comparable log Koc
values. Thus, the substances are expected to have a similar
environmental fate and ecotoxicity profile.
In accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5, grouping
and read-across the target substance Fatty acids, C18 unsaturated, ethyl
& methyl esters (EC 941-981-3) is considered not harmful to aquatic
organisms based on the results of the available read across studies
conducted with fish, aquatic invertebrates and algae and long-term
results on toxicity to aquatic invertebrates up to the limit of water
solubility.
The existing data on the target substance substance Fatty acids, C18 unsaturated, ethyl & methyl esters (EC 941-981-3) indicate that the substance is not acutely toxic to fish and aquatic invertebrates. Comparable results were obtained in a short-term toxicity study on Cyprinus carpio conducted with Fatty acids, safflower-oil, ethyl esters (CAS 91051-53-5). The substance is not acutely toxic to fish. The acute toxicity to algae was investigated in a study on the source substance Fatty acids, C16-18 and C18-unsatd., iso-Bu esters (CAS 84988-79-4). No effect on the algal biomass was observed in a test assay using the water accommodated fraction (WAF) of the substance in the test solution.
Data on chronic toxicity to Daphnia magna are available for Fatty acids, C16-18 and C18-unsatd., iso-Bu esters (CAS 84988-79-4). No mortality of detrimental effect on the reproduction was determined for the substance (NOELR (21 d) ≥ 100 mg/L).
Data on the toxicity to microorganisms are available for Fatty acids, safflower-oil, ethyl esters (CAS 91051-53-5). Effects of the source substance on the respiration rate of activated sludge were not determined.
The available acute toxicity data of the read-across substances demonstrate that toxic effects of the target substance Fatty acids, C18 unsaturated, ethyl & methyl esters (EC 941-981-3) up to the limit of water solubility are not likely. Consequently, additional acute and chronic testing is omitted. Based on the results from structurally related read-across substances (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) it can be concluded that Fatty acids, C18 unsaturated, ethyl & methyl esters (EC 941-981-3) has no toxic effect on freshwater organisms up to the limit of the water solubility (WS ≥0.021 mg/L)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.