Registration Dossier
Registration Dossier
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EC number: 255-464-9 | CAS number: 41621-49-2
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro cytogenicity / chromosome aberration study in mammalian cells
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- SIDS INITIAL ASSESSMENT PROFILE for 2-aminoethanol
- Author:
- OECD
- Year:
- 2 013
- Bibliographic source:
- OECD SIDS INITIAL ASSESSMENT PROFILE
Materials and methods
- Principles of method if other than guideline:
- Data published. No detailed information about principles of method are available.
- GLP compliance:
- not specified
- Remarks:
- Data published. No detailed information about GLP compliance.
- Type of assay:
- other: In vitro mammalian chromosome aberration test
Test material
- Reference substance name:
- 2-aminoethanol
- EC Number:
- 205-483-3
- EC Name:
- 2-aminoethanol
- Cas Number:
- 141-43-5
- Molecular formula:
- C2H7NO
- IUPAC Name:
- 2-aminoethanol
- Test material form:
- liquid
Constituent 1
Results and discussion
Test results
- Species / strain:
- hepatocytes: rat hepatocytes
- Metabolic activation:
- not specified
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not specified
Applicant's summary and conclusion
- Conclusions:
- 2-aminoethanol (the neutral form of Ethanolaminium cation) was negative in vitro cytogenicity / chromosome aberration study in mammalian cells.
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