5-hexyldihydro-5-methylfuran-2(3H)-one

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015-10-28 to 2015-10-29

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: CIPAC MT 1: Freezing Point

Version / remarks:

2009

Deviations:

no

GLP compliance:

no

Remarks:

The study was conducted under supervision of a quality assurance unit which had ensured e.g instrumentation validation, reagent/materials certification, analyst certification and providing standard operating procedures.

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

-14.2 °C

Atm. press.:

1 008 hPa

Decomposition:

no

Sublimation:

no

During the cooling phase, an exothermal effect was observed in the temperature range of approx. -50 to -15 °C, which can be associated with the freezing of the test item.

During the heating phase a distinct endothermic effect was observed in the temperature range of -15 to 0 °C, which can be associated with the melting of the test item. As the onset temperatures in both tests deviate by less than 0.5 K from their mean value of -14.22 °C, the test item has a melting point of -14.2 °C.

The test item showed a second endothermic signal in the temperature range of approx. 170 - 310 °C that can be associated with the boiling of the test item.

No further thermal effects were observed up to the maximum test temperature of 500 °C.

 

Conclusions:

The melting point of the test item was -14.2 °C at 1008 hPa.

Executive summary:

A study was conducted according to OECD test guideline 102, Regulation (EC) No 440/2008 method A.1 and EPA OCSPP test guideline 830.7200 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere. Two tests with about 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a liquid at ambient conditions. Therefore the crucibles were cooled down from ambient temperature to -100 °C with a constant cooling rate of 0.25 K/min under an inert atmosphere. After a waiting period of 30 min at -100 °C, the temperature was increased up to 500 °C at a constant heating rate of 10 K/min. During the cooling phase, an exothermal effect was observed in the temperature range of approx. -50 to -15 °C, which can be associated with the freezing of the test item. During the heating phase a distinct endothermic effect was observed in the temperature range of -15 to 0 °C, which can be associated with the melting of the test item. As the onset temperatures in both tests deviate by less than 0.5 K from their mean value of -14.22 °C, the test item has a melting point of -14.2 °C. No observations were made which cause doubt on the validity of the outcome of the study.

Description of key information

The melting point of the test item was -14.2 °C at 1008 hPa.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

-14.2 °C

Additional information

A study was conducted according to OECD test guideline 102, Regulation (EC) No 440/2008 method A.1 and EPA OCSPP test guideline 830.7200 to determine the melting point of the test item using differential scanning calorimetry. Two tests with about 16 mg of the test item were performed. Crucibles were cooled down from ambient temperature to -100 °C with a constant cooling rate of 0.25 K/min and heated up to 500 °C at a constant heating rate of 10 K/min. During the cooling phase, an exothermal effect was observed in the temperature range of approx. -50 to -15 °C, which can be associated with the freezing of the test item. During the heating phase a distinct endothermic effect was observed in the temperature range of -15 to 0 °C, which can be associated with the melting of the test item. The mean value was determined to be -14.22 °C, therefore the test item has a melting point of -14.2 °C.