Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Remarks:
i.v. mice
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: only short abstract available

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Howard Hall

Materials and methods

Principles of method if other than guideline:
intravenous injection of 1% solution of DPS

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium 3-[[(dimethylamino)thioxomethyl]thio]propanesulphonate
EC Number:
242-644-7
EC Name:
Sodium 3-[[(dimethylamino)thioxomethyl]thio]propanesulphonate
Cas Number:
18880-36-9
Molecular formula:
C6H13NO3S3.Na
IUPAC Name:
sodium 3-[(dimethylcarbamothioyl)sulfanyl]propane-1-sulfonate
Test material form:
not specified

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
TEST ANIMALS
- Source : no data
- Age at study initiation : no data
- Weight at study initiation : 20 g
- Fasting period before study : no data
- Housing : no data
- Diet (e.g. ad libitum) : no data
- Water (e.g. ad libitum) : no data
- Acclimation period : no data

ENVIRONMENTAL CONDITIONS
- Temperature (°C) : no data
- Humidity (%) : no data
- Air changes (per hr) : no data
- Photoperiod (hrs dark / hrs light) : no data

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Doses:
500 mg/kg ( 1.0 mL of a 1% solution/20-gram mouse)
No. of animals per sex per dose:
no data
Control animals:
not specified
Details on study design:
no data

Results and discussion

Any other information on results incl. tables

no untoward effects

Applicant's summary and conclusion