Registration Dossier
Registration Dossier
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EC number: 246-730-5 | CAS number: 25198-22-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- May 29, 1998
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- No information on composition available. The test was conducted on a similar substance. Further details were reported in the attachment at section 13.
- Principles of method if other than guideline:
- Only short abstract available, no further information on the method used.
- GLP compliance:
- not specified
- Test organisms (species):
- activated sludge
- Water media type:
- freshwater
- Total exposure duration:
- 3 h
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 4 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- EC50 (3h) = 4 mg/l
- Executive summary:
Method
The test on "Toxicity to microorganisms" was conducted with an unspecified method as only short abstract is available for this study.
Conclusion
EC50 (3h) = 4 mg/l
- Endpoint:
- toxicity to microorganisms
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Study period:
- August 08, 1989
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- No information on composition available. The test was conducted on a similar substance. Further details were reported in the attachment at section 13.
- Principles of method if other than guideline:
- Only short abstract available. No information about the method used.
- GLP compliance:
- not specified
- Details on sampling:
- - Concentrations: 19.5, 39, 78, 156, 312 mg/l
- Test organisms (species):
- other: No information available
- Total exposure duration:
- 3 h
- Test temperature:
- 25 °C
- pH:
- 7.1 - 7.2
- Dose descriptor:
- EC10
- Effect conc.:
- ca. 40 mg/L
- Remarks on result:
- other: No further information available
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 77 mg/L
- Remarks on result:
- other: No further information available
- Dose descriptor:
- other: EC90
- Effect conc.:
- ca. 213 mg/L
- Remarks on result:
- other: No further information available
- Validity criteria fulfilled:
- not specified
- Conclusions:
- EC10 = 40 mg/l
EC50 = 77 mg/l
EC90 = 213 mg/l - Executive summary:
Method
The test was conducted with an unspecified method as only short abstract is available for this study. No information on the composition is available.
Conclusion
EC10 = 40 mg/l
EC50 = 77 mg/l
EC90 = 213 mg/l
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- March 25, 1976
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Principles of method if other than guideline:
- Internal method 58
- GLP compliance:
- not specified
- Total exposure duration:
- 3 h
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 50 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Validity criteria fulfilled:
- not specified
- Conclusions:
- EC50 = 50 mg/l
- Executive summary:
Only short abstract available.
EC50 = 50 mg/l
Referenceopen allclose all
Only short abstract available. No further information available
Only short abstract available. No further information available.
Description of key information
LC50 = 4 mg/l
Key value for chemical safety assessment
- EC50 for microorganisms:
- 4 mg/L
Additional information
The test substance was tested for its toxicity to microorganisms. No information on the composition and method used for the execution of the study is available.
The LC50 value calculated on the substance in itself was 4 mg/l after 3 hours. To support this information a test on an analogue molecule, a different salification of the same core structure (Similar Substance 01) is available. Further information regardig the acceptability of the Read Across is reported in the attachment at section 13.
The test on the Similar Substance 01 was determined with an unknown method. The LC50 value observed during this test was 77 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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