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EC number: 930-964-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
Monochloroacetic acid: Supporting studies: experimental results from publications.
Key value for chemical safety assessment
Additional information
Monochloroacetic acid:
Supporting studies: experimental results from publications:
A group of Pseudomonas-like bacteria decomposed monochloroacetic acid readily in media with yeast extract, peptone, or amino acids. The organisms are able to grow and produce chloride in the basal medium plus test substance, but the growth is slow and irregular. Further addition of 0.05% yeast extract results in rapid and vigorous growth (uniform turbidity and 89 -97% ionization of the chlorine) within 3 weeks. Peptone has a similar effect. The effect of peptone or yeast extract can be replaced by numerous amino acids (glycine, alanine, leucine, arginine, aspartic acid, asparagine, glutamic acid, lysine, histidine, cysteine, or methionine) in a concentration of 0.02%. Vitamins (thiamine, nicotinic acid, biotin, B12 have no appreciable effect. The organisms seemed to be more active in the soil than in vitro.
Strains of Trichoderma viride, Clonostachys sp. and Acrostalagmus sp. were found able to decompose monochloroacetic acid with liberation of chloride ions when grown in media with glucose, cellulose or xylan as additional carbon source. Several fungi, among them strains of T. viride, produced small amounts of chloride from monochloroacetic acid, while a considerable greater number of fungi were inactive.
Three groups of bacteria: Pseudomonas dehalogenans, Arthrobacter sp. and Agrobacterium sp., are able to dissimilate monochloroacetic acid with release of the chlorine in ionic form. Ps. dehalogenans displays the strongest activity with monochloroacetic acid. The last two groups of bacteria are remarkable by their very poor growth in routine media and their failure to utilize carbohydrates. Chloride production by all three groups of bacteria was strongly accelerated by continuous shaking of the culture and was accompanied by cell growth.
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