Hexyl chloroformate

PBT assessment

PBT assessment: overall result

PBT status:

the substance is not PBT / vPvB

Justification:

The parent substance hexyl chloroformate was determined to be not readily biodegradable in a screening study according to ISO 14593 (CO2-headspade test) and therefore the substance itself does not meet the screening criterion of non-P/non-vP properties. However, based on information available for chloroformates category members in general and the close structural analogue 2 -ethylhexyl chloroformate in specific, the substance may be expected to be subject to very rapid hydrolysis (half-live in the order of minutes rather than hours). The expected degradation products are hexanol (CAS 111 -27 -3), hydrogen chloride (CAS 7647 -01 -0) and carbon dioxide (CAS 124 -38 -9). As the PBT/vPvB criteria of Annex XIII do not apply to inorganic substances only hexanol is further assessed for its PBT/vPvP properties.

Hexanol was found to be readily biodegradable in a screening study according OECD 301D (Closed Bottle Test) and therewith meets the screening criterion for non-P/non-vP properties. Altogether, the substance and its degradation products are assessed to be "not P/vP". For hexanol a log Kow value of 2.03 was determined with EPISuite (EPISuite experimental database). Therefore, hexanol is assessed to be "not B/vB". Finally, hexanol is assessed to be "not T" as the available (NOEC) / EC10 values for aquatic organisms are not <0.01 mg/L nor does it meet the criteria for classification as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), toxic for reproduction (category 1A, 1B or 2) or is there evidence of other chronic toxicity (STOT RE 1, or STOT RE 2).