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EC number: 406-880-6 | CAS number: 88917-22-0 ACETATE DPMA ACROSOLV; ACROSOLV DPMA ACETAT; ACROSOLV DPMA ACETATE; DOWANOL DPMA; DOWANOL DPMA GLYCOL ETHER; DOWANOL DPMA GLYKOL ETHER; ETHER DE GLYCOL DPMA DOWANOL
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Three biodegradation screening studies (BOD tests) are available for dipropylene glycol methyl ether acetate (DPMA). In addition two biodegradation screening studies for the structurally related compounds dipropylene glycol methyl ether (DPM) and propylene glycol methyl ether acetate (PMA) are available as supporting studies.
Key value for chemical safety assessment
Additional information
The biodegradation of dipropylene glycol methyl ether acetate (DPMA) was investigated in three different studies: a modified ready biodegradation test (Dow, 1996), a MITI test (Dow, 2000) and a BOD test (Dow, 1983). The ready biodegradation of DPMA was assessed in a modified 301 D closed bottled test with pre-adapted inoculum. The O2 consumption reached 58% and 84% after 28 days inoculated with DPMA at 7.5 mg/L and 3.5 mg/L respectively, indicating a high potential for biodegradation. In another study (Dow, 1983), the BOD after 28 days was 67% of the ThOD in industrial inoculum, while 9% BOD was observed in municipal inoculum. In the third study (MITI test; Dow, 2000), the level of biodegradation was 12% after 7 days and 16% after 28 days. Analytical determination of the DPMA and its primary metabolite dipropylene glycol methyl ether (DPM) indicate a complete primary degradation of DPMA to DPM and acetate. The primary degradation most likely occurred in the first 7 days of the experiment when the greatest increase in BOD was observed, which is expected to relate to the complete degradation of acetate. The ultimate biodegradation of DPM was, however, not observed in this test system, despite DPM reaching the criteria for ready biodegradation when tested individually (Dow 1998). Based upon its structural similarity to propylene glycol methyl ether acetate (PMA), DPMA is not considered to be persistent. Both PMA and PM, the corresponding propylene glycol methyl ether, have shown rapid biodegradation. For example, rapid degradation of PMA to PM and acetate has been observed in 3 soil types. The degradation half-life of PMA was<1 day, with the subsequent degradation (i.e. mineralisation) of the formed PM within 3 days (Dow, 1995). Since DPMA is structurally similar to PMA, DPMA is expected to degrade to DPM and acetate. Complete primary degradation of DPMA to DPM and acetate was observed in the MITI test (Dow, 2000). Once DPM is formed, full mineralisation can be expected as DPM has been shown to be readily biodegradable in the OECD 301F Manometric Respirometry test. The test methodology used does not allow the conclusion that DPMA is “readily degradable”. However, based on the high levels of biodegradation observed in a modified ready biodegradation test with pre-adapted inoculum and the rapid primary degradation of DPMA to DPM, DPMA can be classified as “inherently biodegradable fulfilling the criteria”.
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