Registration Dossier
Registration Dossier
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EC number: 459-990-1 | CAS number: 52411-34-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, B.3
- GLP compliance:
- yes
- Limit test:
- yes
Test animals
- Species:
- other: rat, Sprague-Dawley Hsd:(SD)
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- other: Angeteigt mit 0,3 ml Tylose (0,5 % in Wasser) "ENGLISH" 0.5 g Bis-(minophenoxy)ethan was moistened with 0.3 ml Tylose.
- Duration of exposure:
- 24 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: Während der gesamten Studiendauer traten weder Todesfälle noch sonstige Effekte auf. Bei einem weiblichen Tier war das Körpergewicht in der ersten Woche leicht reduziert, am Ende der Studie war das Gewicht jed
- Gross pathology:
- Effects on organs:
Bei der Sektion der Tiere wurden keine makroskopisch
sichtbaren Effekte festgestellt.
"ENGLISH"
The animals killed at the end of the observation period
showed no macroscopically visible changes. - Other findings:
- Signs of toxicity (local):
Es wurde keine Reizung festgestellt.
"ENGLISH"
The skin of the animals showed no signs of irritation.
--- 4.1.30 Symptomatik, lokal>
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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