1,1-cyclohexanediacetic acid monoamide

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2003

Reliability:

2 (reliable with restrictions)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2003

Report date:

2003

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method C.3 (Algal Inhibition test)

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

1,1-cyclohexanediacetic acid monoamide

EC Number:

449-430-4

EC Name:

1,1-cyclohexanediacetic acid monoamide

Cas Number:

99189-60-3

Molecular formula:

C10H17NO3

IUPAC Name:

2-[1-(carbamoylmethyl)cyclohexyl]acetic acid

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

not specified

Test organisms

Test organisms (species):

Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:

static

Water media type:

not specified

Limit test:

yes

Total exposure duration:

72 h

Test conditions

pH:

adjusted 7.9

Results and discussion

Effect concentrations

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth rate

Remarks:

and biomass

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

The 72 hour EC50 of the inhibition of the algal biomass and the growth rate were both clearly above the concentration of 100mg/L.