Registration Dossier
Registration Dossier
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EC number: 200-842-0 | CAS number: 75-12-7
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- other: QSAR using the OECD Tooolbox
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: QSAR, no experimental study.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
- Principles of method if other than guideline:
- not applicable
- GLP compliance:
- no
- Type of study:
- other: QSAR using the OECD Tooolbox
Test material
- Reference substance name:
- Formamide
- EC Number:
- 200-842-0
- EC Name:
- Formamide
- Cas Number:
- 75-12-7
- Molecular formula:
- CH3NO
- IUPAC Name:
- formamide
Constituent 1
Results and discussion
In vivo (LLNA)
Results
- Remarks on result:
- no indication of skin sensitisation based on QSAR/QSPR prediction
Any other information on results incl. tables
The OECD Toolbox application, which was used to to evaluate sensitisation QSAR considerations, did not indicate a sensisation potential. Acetamide (CAS 60-35-5) and N,N-dimethylformamide (CAS 68-12-2) were identified as related substances, and negative experimental data is available for both of these. OECD SIDS documents for N,N-dimethylformamide (CAS 68-12-2) are publicly available.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
- Executive summary:
T
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