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Diss Factsheets
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EC number: 210-483-1 | CAS number: 616-45-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in soil
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study based on scientific principals, sufficiently documented.
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Field test with 3 different soil types
- GLP compliance:
- not specified
- Test type:
- laboratory
- Radiolabelling:
- yes
- Oxygen conditions:
- not specified
- Soil classification:
- not specified
- Soil no.:
- #1
- Soil type:
- clay
- Soil no.:
- #2
- Soil type:
- sand
- Soil no.:
- #3
- Soil type:
- loam
- Soil No.:
- #1
- Initial conc.:
- 1.7 mg/kg soil d.w.
- Based on:
- act. ingr.
- Soil No.:
- #2
- Initial conc.:
- 1.7 mg/kg soil d.w.
- Based on:
- act. ingr.
- Soil No.:
- #3
- Initial conc.:
- 1.7 mg/kg soil d.w.
- Based on:
- act. ingr.
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Temp.:
- 20 °C
- Details on experimental conditions:
- Elimination of N-methylpyrrolidone (NMP) from three types of soils (clay, loam, and sand) placed in mini-vials was examined. 10-g soil samples (n = 3) were removed at time intervals of 0, 1, 3, 7, 14, 21, and 28 days and 2 and 3 months and extracted (methanol) for analysis.
- Soil No.:
- #1
- DT50:
- 4 d
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: clay
- Soil No.:
- #2
- DT50:
- 11.5 d
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: sand
- Soil No.:
- #3
- DT50:
- 8.7 d
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: loam
- Transformation products:
- not measured
- Evaporation of parent compound:
- not specified
- Volatile metabolites:
- not specified
- Residues:
- yes
- Details on results:
- After 21 d, the levels of extractable NMP were below 0.1 mg/kg soil.
- Conclusions:
- The test substance N-methylpyrrolidone (NMP) is eliminated in soils. Calculated half-lifes are in the range of 4.0 to 11.5 days.
- Executive summary:
Elimination of N-methylpyrrolidone (NMP) from three types of soils (clay, loam, and sand) placed in mini-vials was examined. 10 -g soil samples (n = 3) were removed at time intervals of 0, 1, 3, 7, 14, 21, and 28 days and 2 and 3 months and extracted (methanol) for analysis. After 21 d, the levels of extractable NMP were below 0.1 mg/kg soil (=> 90% degradation).
Calculated half-lifes for N-methylpyrrolidone (NMP) are 4.0, 8.7 and 11.5 days for clay, loam and sand, respectively.
Reference
RS-Freetext:
Elimination half-lives of N-methylpyrrolidone (NMP) in clay, loam and sand were about 4.0; 8.7, and 11.5 days, resp.
After 21 d, the level of extractable N-methylpyrrolidone (NMP) were below 0.1 mg/kg soil (=> 90 % degradation).
Description of key information
The test substance is eliminated in soils. Calculated half-lifes are in the range of 4.0 to 11.5 days.
Key value for chemical safety assessment
- Half-life in soil:
- 11.5 d
Additional information
The test substance is eliminated in soils. Calculated half-lifes are in the range of 4.0 to 11.5 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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