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EC number: 264-705-7 | CAS number: 64147-40-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Not irritating to skin or eyes. No significant respiratory exposure expected since the substance is non-volatile and has a low vapour pressure.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Data is available for substances representative of the constituents of castor oil, dehydrated.
Skin irritation
As summarised in CIR (2007), castor oil was tested for skin irritation by numerous authors. Undiluted castor oil was irritating to rabbit skin in one study (Motoyoshi et al., 1979), slightly or not irritating irritating in others (Rantuccio et al., 1981; Guillot et al., 1979), mildly irritating to guinea-pig and rat skin (Motoyoshi et al., 1979; Butcher, 1950) but not irritating to miniature swine skin (Motoyoshi et al., 1979).
Other glycerides with varying fatty acid chain lengths such as palm oil (C16-18 and C18-unsatd.), fully hydrogenated cottonseed oil (C16-18), as well as coconut, fully hydrogenated coconut and palm kernel oil (C8-18 and C18-unsatd.) were all not to mildly irritating in occlusive or semi-occlusive testing in rabbit (CIR, 2000; CIR, 2001; CIR, 1986; IUCLID, 2000b).
Adducts formed by glycerides similar to those tested above are not expected to have higher skin irritation potential than the individual glycerides. Their presence in castor oil, dehydrated will therefore not contribute significantly to the skin irritation effects.
Overall, the weight of evidence suggests that castor oil, dehydrated is not irritating skin.
Eye irritation
The eye irritation potential of undiluted castor oil was tested in rabbit eye by three different authors (Carpenter and Smyth, 1946; Guillot et al., 1979; Behrens-Baumann et al.,1986). The results indicated that the substance was not to slightly irritating.
Palm oil (C16-18 and C18-unsatd.), fully hydrogenated cottonseed oil (C16-18), as well as coconut and fully hydrogenated coconut oil (C8-18 and C18-unsatd.) were all mildly to minimally irritating to rabbit eye in standard testing (CIR, 2000, CIR, 2001; CIR, 1986).
Adducts formed by glycerides similar to those tested above are not expected to have higher eye irritation potential than the individual glycerides. Their presence in castor oil, dehydrated will therefore not contribute significantly to the eye irritation effects.
Overall, the weight of evidence suggests that castor oil, dehydrated is not irritating the eyes.
Respiratory irritation
The subtance is non-volatile liquid with a low vapour pressure (7.43 × 10-5 Pa at 20°C). In conditions where aerosol or droplets may be formed (e.g. spray applications), appropriate respiratory protection is recommended as a risk management measure.
Justification for selection of skin irritation / corrosion endpoint:
No one study was selected since the overall weight of evidence demostrates that the substance is not irritating to the skin.
Justification for selection of eye irritation endpoint:
No one study was selected since the overall weight of evidence demostrates that the substance is not irritating to the eyes.
Justification for classification or non-classification
Eye and skin irritation studies were conducted with fats and glyceridic oils in the form of castor oil and rincinoleic acid. Overall, the substance is assessed to be not irritating to skin and eyes.
Exposure via the inhalation route and consequent respiratory irritation is not expected given the physical-chemical properties (non volatile liquid and low vapour pressure (7.43 × 10-5Pa at 20°C))
of the substance.Based on the above information, the substance does not require to be classified for irritation properties according to Directive 67/548/EC or Regulation 1272/2008/EC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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