Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-785-7 | CAS number: 99-76-3
Endpoint summary
Administrative data
Description of key information
Additional information
The short-term toxicity to fish was determined in a study conducted by the Ministry of the Environment in Japan based on OECD-GLP standard and OECD guidelines. The LC50 after 96 hours in the species Oryzias latipes was determined to be 59.5 mg/L.
The toxicity to aquatic algae (Pseudokirchneriella subcapitata) was determined in a study based on an ISO guideline. The EC50 after 72 hours was determined to be 91 mg/L.
The short-term toxicity to Daphnia magna was determined in a study based on an ISO guideline. The EC50 after 48 hours was determined to be 11.2 mg/L.
Determination of effects in a long term toxicity study to aquatic invertebrates (OECD 211) leads to the following values:
EC 50 Reproduction (21 days): 5.32 mg/L
No Observed Effect Concentration on Reproduction (NOEC) : 0.20 mg/L
Lowest Observed Effect Concentration on Reproduction (LOEC) : 0. 81 mg/L
EC50 (mortality) for parental daphnia (21days): 0.89 mg/L
In a first zebrafish sexual development test according to OECD guideline 234 the lowest calulated NOEC was 0.11 mg/L (mean measured concentration) based on the parameter total survival.
Since this test was not valid a second test was carried out according to OECD guideline 234. The lowest calulated NOEC was 24 µg/L (mean measured concentration) based on the parameter total survival.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
