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Physical & Chemical properties

Melting point / freezing point

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Description of key information

>235 to <246.9 °C with decomposition.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
246.9 °C

Additional information

The melting point for Prednisolone ranges from >235 (Hawley's Condensed Chemical Dictionary 14th Edition.) to <246.9°C at 101.3 kPa (Farmabios analysis MP36892). Decomposition was quoted from almost all experimental and bibliographic sources. The melting point was determined according to ASTM D1519, equivalent to European Pharmacopeia (Ph.Eur.) 2.2.60.