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Diss Factsheets
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EC number: 239-557-1 | CAS number: 15520-11-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
One short-term result on fish toxicity is available for the bis(4-tert-butylcyclohexyl) peroxydicarbonate. The 96-h LC50 was determined to be 704 mg/L. Although this result is considered to be of limited reliability no repeat test was conducted as the endpoints "short-term toxicity testing on invertebrates" and "growth inhibition study aquatic plants" are more sensitive and therefore critical for classification and labelling as well as for the risk assessment.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 704 mg/L
Additional information
One experimental result (reliability Klimisch 3) is available for the endpoint acute toxicity to fish. In the 96-h acute toxicity study according to OECD guideline 203, approximately 3 month old rainbow trout (Oncorhynchus mykiss) were exposed to bis(4-tert-butylcyclohexyl) peroxydicarbonate at nominal concentrations of 0 (control and solvent control),100, 180, 320, 560 and 1000mg/L under semi-static conditions.
The 96-h LC50was calculated to be 704 mg/L. The NOEC value (based on mortality) was 320 mg/L. Sublethal effects of darkened pigmentation were observed in three fish of the groups exposed to 1000 mg/L of test substance.
However, the study is deemed to be unreliable as the test design shows significant methodological deficiencies. Undissolved test material could be observed in the test vessels which could have been taken up by the test organisms by ingestion. In addition, the actual test substance concentrations were not measured so that the actual exposure concentrations are not known.
However, fish are typically the least sensitive species against organic peroxides (cf. position paper attached to IUCLID section 13) an additional vertebrate study for this endpoint is considered to be unnecessary.
The results of the existing acute toxicity study in fish study are deemed adequate for classification purposes. The requirements for classification and labelling, i.e. availability of results for trophic levels, are fulfilled. The results on short-term toxicity in invertebrates and growth inhibition to aquatic plants are more sensitive compared to the acute toxicity in fish and are therefore critical for classification and labelling as well as for the risk assessment. Thus, particularly taking into account animal welfare considerations, a repeat study to obtain new data on the short-term toxicity on fish is deemed unnecessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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